TY - JOUR
T1 - An examination of subgroup classification in irritable bowel syndrome patients over time
T2 - a prospective study
AU - Penny, Kay
AU - Smith, Graeme
AU - Ramsay, D
AU - Steinke, D
AU - Kinnear, Moira
AU - Penman, Ian
PY - 2008/12/1
Y1 - 2008/12/1
N2 - Irritable bowel syndrome (IBS) is a complex functional gastrointestinal disorder which to date remains poorly understood. Therapies for irritable bowel syndrome (IBS) patients are usually aimed at relieving the predominant symptom; however, little evidence exists as to whether or not the predominant symptom changes with time. Nurses are becoming increasingly involved in the assessment and management of IBS patients. To categorise IBS patients into one of three sub-types, namely diarrhoea-predominant, constipation-predominant and a third group who alternate between the two, and to investigate changes in patient sub-type classification over time. The general population of the United Kingdom (UK). A cohort of 494 IBS patients, with a confirmed Rome II classification diagnosis, was recruited in the UK. Patients’ IBS symptoms were recorded throughout a 26-week period. Proportions of individuals in each IBS subgroup were calculated and probabilities of moving from one subgroup to another between consecutive weeks were estimated. The percentage of patients given an overall subgroup classification of diarrhoea-predominant IBD (D-IBS) is 40.9%; 58.1% and 1% were classified as belonging to the alternator (A-IBS) and constipation-predominant (C-IBS) subgroups, respectively. classified as an alternator or as diarrhoea-predominant have a high probability (0.67 and 0.71, respectively) of remaining in the same subgroup; however this probability is lower for constipation-predominant patients (0.35). Although many patients remain in the same IBS subgroup classification over time, there are individuals whose subgroup classification varies. As such, patients’ IBS subgroup classification should be reviewed regularly and treatment adjusted accordingly in order to optimise patient care.
AB - Irritable bowel syndrome (IBS) is a complex functional gastrointestinal disorder which to date remains poorly understood. Therapies for irritable bowel syndrome (IBS) patients are usually aimed at relieving the predominant symptom; however, little evidence exists as to whether or not the predominant symptom changes with time. Nurses are becoming increasingly involved in the assessment and management of IBS patients. To categorise IBS patients into one of three sub-types, namely diarrhoea-predominant, constipation-predominant and a third group who alternate between the two, and to investigate changes in patient sub-type classification over time. The general population of the United Kingdom (UK). A cohort of 494 IBS patients, with a confirmed Rome II classification diagnosis, was recruited in the UK. Patients’ IBS symptoms were recorded throughout a 26-week period. Proportions of individuals in each IBS subgroup were calculated and probabilities of moving from one subgroup to another between consecutive weeks were estimated. The percentage of patients given an overall subgroup classification of diarrhoea-predominant IBD (D-IBS) is 40.9%; 58.1% and 1% were classified as belonging to the alternator (A-IBS) and constipation-predominant (C-IBS) subgroups, respectively. classified as an alternator or as diarrhoea-predominant have a high probability (0.67 and 0.71, respectively) of remaining in the same subgroup; however this probability is lower for constipation-predominant patients (0.35). Although many patients remain in the same IBS subgroup classification over time, there are individuals whose subgroup classification varies. As such, patients’ IBS subgroup classification should be reviewed regularly and treatment adjusted accordingly in order to optimise patient care.
KW - irritable bowel syndrome
KW - subgroup classification
KW - subgroup change
UR - http://www.sciencedirect.com/science/article/pii/S0020748908000953
U2 - 10.1016/j.ijnurstu.2008.04.004
DO - 10.1016/j.ijnurstu.2008.04.004
M3 - Article
SN - 0020-7489
VL - 45
SP - 1715
EP - 1720
JO - International Journal of Nursing Studies
JF - International Journal of Nursing Studies
IS - 12
ER -