An electrochemical SARS-CoV-2 biosensor inspired by glucose test strip manufacturing processes

Vincent J. Vezza; Adrian Butterworth; Perrine Lasserre; Ewen O. Blair; Alexander MacDonald; Stuart Hannah; Christopher Rinaldi; Paul A. Hoskisson; Andrew C. Ward; Alistair Longmuir; Steven Setford; Eoghan C. W. Farmer; Michael E. Murphy; Damion K. Corrigan

doi:10.1039/D1CC00936B

An electrochemical SARS-CoV-2 biosensor inspired by glucose test strip manufacturing processes

Vincent J. Vezza, Adrian Butterworth, Perrine Lasserre, Ewen O. Blair, Alexander MacDonald, Stuart Hannah, Christopher Rinaldi, Paul A. Hoskisson, Andrew C. Ward, Alistair Longmuir, Steven Setford, Eoghan C. W. Farmer, Michael E. Murphy, Damion K. Corrigan

Research output: Contribution to journal › Article › peer-review

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Abstract

Accurate and rapid diagnostic tests are critical to reducing the impact of SARS-CoV-2. This study presents early, but promising measurements of SARS-CoV-2 using the ACE2 enzyme as the recognition element to achieve clinically relevant detection. The test provides a scalable route to sensitive, specific, rapid and low cost mass testing.

Original language	English
Number of pages	4
Journal	Chemical Communications
DOIs	https://doi.org/10.1039/D1CC00936B
Publication status	Published - 12 Mar 2021

Keywords

electrochemical sensors
electrochemical impedance spectroscopy (EIS)
SARS-CoV-2
COVID-19

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EPSRC Centre for Doctoral Training in Medical Devices and Health Technologies | Vezza, Vincent
Corrigan, D., Hoskisson, P. & Vezza, V.
EPSRC (Engineering and Physical Sciences Research Council)
1/10/16 → 1/04/21
Project: Research Studentship - Internally Allocated

Cite this

Vezza, V. J., Butterworth, A., Lasserre, P., Blair, E. O., MacDonald, A., Hannah, S., Rinaldi, C., Hoskisson, P. A., Ward, A. C., Longmuir, A., Setford, S., Farmer, E. C. W., Murphy, M. E., & Corrigan, D. K. (2021). An electrochemical SARS-CoV-2 biosensor inspired by glucose test strip manufacturing processes. Chemical Communications. https://doi.org/10.1039/D1CC00936B

Vezza, Vincent J. ; Butterworth, Adrian ; Lasserre, Perrine ; Blair, Ewen O. ; MacDonald, Alexander ; Hannah, Stuart ; Rinaldi, Christopher ; Hoskisson, Paul A. ; Ward, Andrew C. ; Longmuir, Alistair ; Setford, Steven ; Farmer, Eoghan C. W. ; Murphy, Michael E. ; Corrigan, Damion K. / An electrochemical SARS-CoV-2 biosensor inspired by glucose test strip manufacturing processes. In: Chemical Communications. 2021.

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title = "An electrochemical SARS-CoV-2 biosensor inspired by glucose test strip manufacturing processes",

abstract = "Accurate and rapid diagnostic tests are critical to reducing the impact of SARS-CoV-2. This study presents early, but promising measurements of SARS-CoV-2 using the ACE2 enzyme as the recognition element to achieve clinically relevant detection. The test provides a scalable route to sensitive, specific, rapid and low cost mass testing. ",

keywords = "electrochemical sensors, electrochemical impedance spectroscopy (EIS), SARS-CoV-2, COVID-19",

author = "Vezza, {Vincent J.} and Adrian Butterworth and Perrine Lasserre and Blair, {Ewen O.} and Alexander MacDonald and Stuart Hannah and Christopher Rinaldi and Hoskisson, {Paul A.} and Ward, {Andrew C.} and Alistair Longmuir and Steven Setford and Farmer, {Eoghan C. W.} and Murphy, {Michael E.} and Corrigan, {Damion K.}",

year = "2021",

month = mar,

day = "12",

doi = "10.1039/D1CC00936B",

language = "English",

journal = "Chemical Communications",

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publisher = "Royal Society of Chemistry",

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An electrochemical SARS-CoV-2 biosensor inspired by glucose test strip manufacturing processes. / Vezza, Vincent J.; Butterworth, Adrian; Lasserre, Perrine ; Blair, Ewen O.; MacDonald, Alexander ; Hannah, Stuart ; Rinaldi, Christopher ; Hoskisson, Paul A.; Ward, Andrew C.; Longmuir, Alistair; Setford, Steven; Farmer, Eoghan C. W.; Murphy, Michael E.; Corrigan, Damion K.

In: Chemical Communications, 12.03.2021.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - An electrochemical SARS-CoV-2 biosensor inspired by glucose test strip manufacturing processes

AU - Vezza, Vincent J.

AU - Butterworth, Adrian

AU - Lasserre, Perrine

AU - Blair, Ewen O.

AU - MacDonald, Alexander

AU - Hannah, Stuart

AU - Rinaldi, Christopher

AU - Hoskisson, Paul A.

AU - Ward, Andrew C.

AU - Longmuir, Alistair

AU - Setford, Steven

AU - Farmer, Eoghan C. W.

AU - Murphy, Michael E.

AU - Corrigan, Damion K.

PY - 2021/3/12

Y1 - 2021/3/12

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AB - Accurate and rapid diagnostic tests are critical to reducing the impact of SARS-CoV-2. This study presents early, but promising measurements of SARS-CoV-2 using the ACE2 enzyme as the recognition element to achieve clinically relevant detection. The test provides a scalable route to sensitive, specific, rapid and low cost mass testing.

KW - electrochemical sensors

KW - electrochemical impedance spectroscopy (EIS)

KW - SARS-CoV-2

KW - COVID-19

U2 - 10.1039/D1CC00936B

DO - 10.1039/D1CC00936B

M3 - Article

JO - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

ER -

An electrochemical SARS-CoV-2 biosensor inspired by glucose test strip manufacturing processes

Abstract

Keywords

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EPSRC Centre for Doctoral Training in Medical Devices and Health Technologies | Vezza, Vincent

Cite this