Amphiphilic network as nanoreactor for enzymes in organic solvents

Nico Bruns, Joerg C. Tiller

Research output: Contribution to journalArticle

169 Citations (Scopus)

Abstract

Enzymes are powerful biocatalysts that work naturally in water but are also active in organic solvents. Here, we present a nanophase-separated amphiphilic network, where an enzyme is entrapped into its hydrophilic domains. A substrate that diffuses into the other, hydrophobic, phase of such a network can access the biocatalyst via the extremely large interface. Entrapped horseradish peroxidase and chloroperoxidase showed dramatically increased activity and operational stability compared to the native enzymes.

Original languageEnglish
Pages (from-to)45-48
Number of pages4
JournalNano Letters
Volume5
Issue number1
DOIs
Publication statusPublished - 1 Jan 2005

Keywords

  • organic solvents
  • biocatalysts
  • horseradish peroxidase

Fingerprint Dive into the research topics of 'Amphiphilic network as nanoreactor for enzymes in organic solvents'. Together they form a unique fingerprint.

  • Cite this