Amphiphilic network as nanoreactor for enzymes in organic solvents

Nico Bruns, Joerg C. Tiller

Research output: Contribution to journalArticle

161 Citations (Scopus)

Abstract

Enzymes are powerful biocatalysts that work naturally in water but are also active in organic solvents. Here, we present a nanophase-separated amphiphilic network, where an enzyme is entrapped into its hydrophilic domains. A substrate that diffuses into the other, hydrophobic, phase of such a network can access the biocatalyst via the extremely large interface. Entrapped horseradish peroxidase and chloroperoxidase showed dramatically increased activity and operational stability compared to the native enzymes.

LanguageEnglish
Pages45-48
Number of pages4
JournalNano Letters
Volume5
Issue number1
DOIs
Publication statusPublished - 1 Jan 2005

Fingerprint

Nanoreactors
Organic solvents
enzymes
Biocatalysts
Enzymes
Chloride Peroxidase
Horseradish Peroxidase
Substrates
water
Water

Keywords

  • organic solvents
  • biocatalysts
  • horseradish peroxidase

Cite this

Bruns, Nico ; Tiller, Joerg C. / Amphiphilic network as nanoreactor for enzymes in organic solvents. In: Nano Letters. 2005 ; Vol. 5, No. 1. pp. 45-48.
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Amphiphilic network as nanoreactor for enzymes in organic solvents. / Bruns, Nico; Tiller, Joerg C.

In: Nano Letters, Vol. 5, No. 1, 01.01.2005, p. 45-48.

Research output: Contribution to journalArticle

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