Amoebicidal compositions for contact lens solutions

Fiona Henriquez; Roderick A.M. Williams; Ronnie Mooney

Amoebicidal compositions for contact lens solutions

Fiona Henriquez (Inventor), Roderick A.M. Williams^* (Inventor), Ronnie Mooney (Inventor)

^*Corresponding author for this work

Civil And Environmental Engineering

Research output: Patent

Abstract

Described herein are pharmaceutical compositions and contact lens solutions comprising an Acanthamoeba encystation inhibitor such as a cationic quaternary ammonium compound and a physiologically or pharmaceutically acceptable carrier or excipient, optionally in combination with an Acanthamoeba cytotoxic agent such as an alkylphosphocholine. Such compositions are suitable for use in the treatment of Acanthamoeba infection or the prevention or treatment of Acanthamoeba keratitis.

Original language	English
Patent number	WO2021028696A1
Filing date	15/08/19
Publication status	Published - 30 Mar 2023

Keywords

Acanthamoeba
contact lens
disinfectant
antimicrobial
quaternary ammonium compound
alkylphosphocholines

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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title = "Amoebicidal compositions for contact lens solutions",

abstract = "Described herein are pharmaceutical compositions and contact lens solutions comprising an Acanthamoeba encystation inhibitor such as a cationic quaternary ammonium compound and a physiologically or pharmaceutically acceptable carrier or excipient, optionally in combination with an Acanthamoeba cytotoxic agent such as an alkylphosphocholine. Such compositions are suitable for use in the treatment of Acanthamoeba infection or the prevention or treatment of Acanthamoeba keratitis.",

keywords = "Acanthamoeba, contact lens, disinfectant, antimicrobial, quaternary ammonium compound, alkylphosphocholines",

author = "Fiona Henriquez and Williams, {Roderick A.M.} and Ronnie Mooney",

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language = "English",

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TY - PAT

T1 - Amoebicidal compositions for contact lens solutions

AU - Henriquez, Fiona

AU - Williams, Roderick A.M.

AU - Mooney, Ronnie

PY - 2023/3/30

Y1 - 2023/3/30

N2 - Described herein are pharmaceutical compositions and contact lens solutions comprising an Acanthamoeba encystation inhibitor such as a cationic quaternary ammonium compound and a physiologically or pharmaceutically acceptable carrier or excipient, optionally in combination with an Acanthamoeba cytotoxic agent such as an alkylphosphocholine. Such compositions are suitable for use in the treatment of Acanthamoeba infection or the prevention or treatment of Acanthamoeba keratitis.

AB - Described herein are pharmaceutical compositions and contact lens solutions comprising an Acanthamoeba encystation inhibitor such as a cationic quaternary ammonium compound and a physiologically or pharmaceutically acceptable carrier or excipient, optionally in combination with an Acanthamoeba cytotoxic agent such as an alkylphosphocholine. Such compositions are suitable for use in the treatment of Acanthamoeba infection or the prevention or treatment of Acanthamoeba keratitis.

KW - Acanthamoeba

KW - contact lens

KW - disinfectant

KW - antimicrobial

KW - quaternary ammonium compound

KW - alkylphosphocholines

UR - https://patents.google.com/patent/US20230102836A1/en

M3 - Patent

M1 - WO2021028696A1

Y2 - 2019/08/15

ER -

Amoebicidal compositions for contact lens solutions

Abstract

Keywords

UN SDGs

Other files and links

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Alkyl-carbon chain length of two distinct compounds and derivatives are key determinants of their anti-Acanthamoeba activities

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