Aminocatalytic preparation of bisindolylalkanes

Timothy J. K. Gibbs, Nicholas C. O. Tomkinson

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

An aminocatalytic method for the formation of bisindolylalkanes, e.g. I (R = Et, cyclopropyl, Ph) is described; the reaction proceeds effectively at ambient temp. in the presence of moisture and air for both aldehyde and ketone substrates and has been applied to the one-step prepn. of a series of naturally-occurring bis- and tris-indolylalkanes.
LanguageUndefined/Unknown
Pages4043-4045
Number of pages3
JournalOrganic and Biomolecular Chemistry
Volume3
Issue number22
DOIs
Publication statusPublished - 2005

Keywords

  • bisindolylalkanes
  • aldehydes
  • ketones

Cite this

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abstract = "An aminocatalytic method for the formation of bisindolylalkanes, e.g. I (R = Et, cyclopropyl, Ph) is described; the reaction proceeds effectively at ambient temp. in the presence of moisture and air for both aldehyde and ketone substrates and has been applied to the one-step prepn. of a series of naturally-occurring bis- and tris-indolylalkanes.",
keywords = "bisindolylalkanes , aldehydes, ketones",
author = "Gibbs, {Timothy J. K.} and Tomkinson, {Nicholas C. O.}",
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pages = "4043--4045",
journal = "Organic and Biomolecular Chemistry",
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Aminocatalytic preparation of bisindolylalkanes. / Gibbs, Timothy J. K.; Tomkinson, Nicholas C. O.

In: Organic and Biomolecular Chemistry, Vol. 3, No. 22, 2005, p. 4043-4045.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Aminocatalytic preparation of bisindolylalkanes

AU - Gibbs, Timothy J. K.

AU - Tomkinson, Nicholas C. O.

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AB - An aminocatalytic method for the formation of bisindolylalkanes, e.g. I (R = Et, cyclopropyl, Ph) is described; the reaction proceeds effectively at ambient temp. in the presence of moisture and air for both aldehyde and ketone substrates and has been applied to the one-step prepn. of a series of naturally-occurring bis- and tris-indolylalkanes.

KW - bisindolylalkanes

KW - aldehydes

KW - ketones

U2 - 10.1039/b513394g

DO - 10.1039/b513394g

M3 - Article

VL - 3

SP - 4043

EP - 4045

JO - Organic and Biomolecular Chemistry

T2 - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

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