Aminocatalytic preparation of bisindolylalkanes

Timothy J. K. Gibbs; Nicholas C. O. Tomkinson

doi:10.1039/b513394g

Aminocatalytic preparation of bisindolylalkanes

Timothy J. K. Gibbs, Nicholas C. O. Tomkinson

Pure And Applied Chemistry

Research output: Contribution to journal › Article › peer-review

40 Citations (Scopus)

Abstract

An aminocatalytic method for the formation of bisindolylalkanes, e.g. I (R = Et, cyclopropyl, Ph) is described; the reaction proceeds effectively at ambient temp. in the presence of moisture and air for both aldehyde and ketone substrates and has been applied to the one-step prepn. of a series of naturally-occurring bis- and tris-indolylalkanes.

Original language	Undefined/Unknown
Pages (from-to)	4043-4045
Number of pages	3
Journal	Organic and Biomolecular Chemistry
Volume	3
Issue number	22
DOIs	https://doi.org/10.1039/b513394g
Publication status	Published - 2005

Keywords

bisindolylalkanes
aldehydes
ketones

Access to Document

10.1039/b513394g

Cite this

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title = "Aminocatalytic preparation of bisindolylalkanes",

abstract = "An aminocatalytic method for the formation of bisindolylalkanes, e.g. I (R = Et, cyclopropyl, Ph) is described; the reaction proceeds effectively at ambient temp. in the presence of moisture and air for both aldehyde and ketone substrates and has been applied to the one-step prepn. of a series of naturally-occurring bis- and tris-indolylalkanes. ",

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AU - Tomkinson, Nicholas C. O.

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AB - An aminocatalytic method for the formation of bisindolylalkanes, e.g. I (R = Et, cyclopropyl, Ph) is described; the reaction proceeds effectively at ambient temp. in the presence of moisture and air for both aldehyde and ketone substrates and has been applied to the one-step prepn. of a series of naturally-occurring bis- and tris-indolylalkanes.

KW - bisindolylalkanes

KW - aldehydes

KW - ketones

U2 - 10.1039/b513394g

DO - 10.1039/b513394g

M3 - Article

VL - 3

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EP - 4045

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

SN - 1477-0520

IS - 22

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