Amidine dications: isolation and [fe]-hydrogenase-related hydrogenation

M.J. Corr, K.F. Gibson, A.R. Kennedy, J.A. Murphy

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

This commmunication demonstrates the preparation, isolation, and full characterization of superelectrophilic salts based on amidine dications in organic solvent, as their triflate salts. These dications are highly activated toward regiospecific reaction with hydrogen gas under mild conditions in the presence of a metal catalyst (Pd/C), mimicking the behavior of the natural substrate, N-5,N-10-methenyltetrahydromethanopterin, in the iron-sulfur cluster-free [Fe]-hydrogenase.
LanguageEnglish
Pages9174-9175
Number of pages2
JournalJournal of the American Chemical Society
Volume131
Issue number26
DOIs
Publication statusPublished - 8 Jul 2009

Fingerprint

Amidines
Hydrogenation
Salts
Hydrogenase
Sulfur
Organic solvents
Hydrogen
Iron
Gases
Metals
Catalysts
Substrates
iron hydrogenase
methenyltetrahydromethanopterin

Keywords

  • cluster-free hydrogenase
  • metal-free hudrogenase
  • methanobacterium-thermautotrophicum
  • active-site
  • N5
  • N10-geometry

Cite this

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abstract = "This commmunication demonstrates the preparation, isolation, and full characterization of superelectrophilic salts based on amidine dications in organic solvent, as their triflate salts. These dications are highly activated toward regiospecific reaction with hydrogen gas under mild conditions in the presence of a metal catalyst (Pd/C), mimicking the behavior of the natural substrate, N-5,N-10-methenyltetrahydromethanopterin, in the iron-sulfur cluster-free [Fe]-hydrogenase.",
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Amidine dications : isolation and [fe]-hydrogenase-related hydrogenation. / Corr, M.J.; Gibson, K.F.; Kennedy, A.R.; Murphy, J.A.

In: Journal of the American Chemical Society, Vol. 131, No. 26, 08.07.2009, p. 9174-9175.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Amidine dications

T2 - Journal of the American Chemical Society

AU - Corr, M.J.

AU - Gibson, K.F.

AU - Kennedy, A.R.

AU - Murphy, J.A.

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KW - metal-free hudrogenase

KW - methanobacterium-thermautotrophicum

KW - active-site

KW - N5

KW - N10-geometry

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