Projects per year
Abstract
This commmunication demonstrates the preparation, isolation, and full characterization of superelectrophilic salts based on amidine dications in organic solvent, as their triflate salts. These dications are highly activated toward regiospecific reaction with hydrogen gas under mild conditions in the presence of a metal catalyst (Pd/C), mimicking the behavior of the natural substrate, N-5,N-10-methenyltetrahydromethanopterin, in the iron-sulfur cluster-free [Fe]-hydrogenase.
Original language | English |
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Pages (from-to) | 9174-9175 |
Number of pages | 2 |
Journal | Journal of the American Chemical Society |
Volume | 131 |
Issue number | 26 |
DOIs | |
Publication status | Published - 8 Jul 2009 |
Keywords
- cluster-free hydrogenase
- metal-free hudrogenase
- methanobacterium-thermautotrophicum
- active-site
- N5
- N10-geometry
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Dive into the research topics of 'Amidine dications: isolation and [fe]-hydrogenase-related hydrogenation'. Together they form a unique fingerprint.Projects
- 2 Finished
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Organic dications: Synthesis, Reactivity and Applications
Murphy, J. (Principal Investigator)
EPSRC (Engineering and Physical Sciences Research Council)
1/09/09 → 30/06/13
Project: Research
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Physical Organic Chemistry: Opportunities In Synthesis, Materials And Pharmaceuticals (Science And Innovation Award)
Murphy, J. (Principal Investigator), Coombs, G. (Co-investigator), Ferguson, A. (Co-investigator) & Florence, A. (Co-investigator)
Scottish Funding Council SFC, EPSRC (Engineering and Physical Sciences Research Council)
1/09/07 → 30/10/12
Project: Research