Altered regulation of cardiac calcium handling proteins in an in vivo rat model of angiotensin-induced hypertension

Zainab O. Olatunji, Zainab Bosakhar, Graeme MacKenzie, Margaret Cunningham, Niall Macquaide, Susan Currie

Research output: Contribution to conferencePosterpeer-review

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Abstract

Hypertension is a major comorbidity in patients with heart failure with preserved ejection fraction (HFpEF), which remains an increasing global challenge. Cardiac remodelling and dysfunction as well as altered calcium (Ca2+) homeostasis are all characteristics of this disease1,2. However, existing models and evidence on the mechanisms driving this form of cardiomyopathy remain contradictory.
Original languageEnglish
Number of pages1
Publication statusPublished - 4 Sept 2023
EventBritish Society for Cardiovascular research Autumn meeting 2023 - University of Oxford
Duration: 4 Sept 20235 Sept 2023

Conference

ConferenceBritish Society for Cardiovascular research Autumn meeting 2023
Period4/09/235/09/23

Keywords

  • hypertension
  • angiotensin
  • in vivo models

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