@article{920cb5944aa440ad875c63b5599d5fea,
title = "Alkene syn dihydroxylation with malonoyl peroxides",
abstract = "Cyclopropyl malonoyl peroxide (1), which can be prepared in a single step from the commercially available diacid, is an effective reagent for the dihydroxylation of alkenes. Reaction of 1 with an alkene in the presence of 1 equiv of water at 40 °C followed by alkaline hydrolysis leads to the corresponding diol (40-93%). With 1,2-disubstituted alkenes, the reaction proceeds with syn selectivity (3:1 to >50:1). A mechanism consistent with the experimental findings that is supported by oxygen-labeling studies is proposed.",
keywords = "benzene, benzenoid compunds, alkene syn dihydroxylation ",
author = "Griffith, {James C} and Jones, {Kevin M} and Sylvain Picon and Rawling, {Michael J} and Kariuki, {Benson M} and Matthew Campbell and Tomkinson, {Nicholas C. O.}",
year = "2010",
month = oct,
day = "20",
doi = "10.1021/ja1066674",
language = "English",
volume = "132",
pages = "14409--14411",
journal = "Journal of the American Chemical Society",
issn = "0002-7863",
publisher = "American Chemical Society",
number = "41",
}