When a sodium (or potassium) reagent is combined with a magnesium one to form a single organometallic bimetallic entity, a special chemistry which cannot be replicated by either individual metal reagent can be obtained. In terms of deprotonative metalation, the mixed alkyl-amido sodium magnesium complex 'Na4Mg2(TMP)6nBu2', where TMP is 2,2,6,6-tetramethylpiperidide, has been shown to be capable of regioselectively deprotonating simple mono-substituted feedstock arenes, some at 2,5 positions and others at 3,5. Here this work is extended to multi-aryl species and heterocycles.
|Number of pages||1|
|Publication status||Published - 15 Jul 2016|
|Event||Gordon Research Conference: Organometallic Chemistry. Newport, Rhode Island USA - Salve Regina University, Newport, RI, United States|
Duration: 10 Jul 2016 → 15 Jul 2016
|Conference||Gordon Research Conference: Organometallic Chemistry. Newport, Rhode Island USA|
|Period||10/07/16 → 15/07/16|
- alkali metal magnesiates
- organic chemistry
O'Hara, C. (2016). Alkali metal magnesiates: reagents for regioselective double metalations. Abstract from Gordon Research Conference: Organometallic Chemistry. Newport, Rhode Island USA, Newport, RI, United States.