Although it is generally accepted that endurance training improves cardiac function after myocardial infarction the sub-cellular mechanisms are uncertain. The present study reports the effects of aerobic endurance training on myocardial mass, myocyte dimensions, contractile function, Ca2+ handling, and myofilament responsiveness to Ca2+ in cardiomyocytes from healthy and failing rat hearts.
- heart failure
Wisløff, U., Loennechen, J. P., Currie, S., Smith, G. L., & Ellingsen, Ø. (2002). Aerobic exercise reduces cardiomyocyte hypertrophy and increases contractility, Ca2+ sensitivity and SERCA-2 in rat after myocardial infarction. Cardiovascular Research, 54(1), 162-174. https://doi.org/10.1016/S0008-6363(01)00565-X