Advancing isotope labeling technologies at AstraZeneca through academic-industrial collaboration

Ryan A. Bragg; Jonas  Bergare; Markus  Artelsmair; William J. Kerr; Troels  Skrydstrup; Charles S.  Elmore

doi:10.1021/acsmedchemlett.5c00338

Advancing isotope labeling technologies at AstraZeneca through academic-industrial collaboration

Ryan A. Bragg^*, Jonas Bergare, Markus Artelsmair, William J. Kerr, Troels Skrydstrup, Charles S. Elmore^*

^*Corresponding author for this work

Pure And Applied Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

Academic-Industrial collaborations have played an important role in developing new synthetic methodologies for the isotope chemistry team at AstraZeneca. In this communication, we present the outcome of two collaborations and illustrate how the innovative methodologies developed through these partnerships have been effectively applied within an AstraZeneca project.

Original language	English
Pages (from-to)	1221-1225
Number of pages	5
Journal	ACS Medicinal Chemistry Letters
Volume	16
Issue number	7
Early online date	20 Jun 2025
DOIs	https://doi.org/10.1021/acsmedchemlett.5c00338
Publication status	Published - 10 Jul 2025

Keywords

collaboration isotopes
carbonylation
tritium
radiolabeling

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10.1021/acsmedchemlett.5c00338

Bragg-etal-ACS-MCL-2025-Advancing-isotope-labeling-technologies-at-AstraZeneca
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Accepted author manuscript, 998 KBLicence: CC BY 4.0

Cite this

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title = "Advancing isotope labeling technologies at AstraZeneca through academic-industrial collaboration",

abstract = "Academic-Industrial collaborations have played an important role in developing new synthetic methodologies for the isotope chemistry team at AstraZeneca. In this communication, we present the outcome of two collaborations and illustrate how the innovative methodologies developed through these partnerships have been effectively applied within an AstraZeneca project.",

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AU - Bragg, Ryan A.

AU - Bergare, Jonas

AU - Artelsmair, Markus

AU - Kerr, William J.

AU - Skrydstrup, Troels

AU - Elmore, Charles S.

PY - 2025/7/10

Y1 - 2025/7/10

N2 - Academic-Industrial collaborations have played an important role in developing new synthetic methodologies for the isotope chemistry team at AstraZeneca. In this communication, we present the outcome of two collaborations and illustrate how the innovative methodologies developed through these partnerships have been effectively applied within an AstraZeneca project.

AB - Academic-Industrial collaborations have played an important role in developing new synthetic methodologies for the isotope chemistry team at AstraZeneca. In this communication, we present the outcome of two collaborations and illustrate how the innovative methodologies developed through these partnerships have been effectively applied within an AstraZeneca project.

KW - collaboration isotopes

KW - carbonylation

KW - tritium

KW - radiolabeling

UR - https://pubs.acs.org/journal/amclct

U2 - 10.1021/acsmedchemlett.5c00338

DO - 10.1021/acsmedchemlett.5c00338

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JF - ACS Medicinal Chemistry Letters

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Advancing isotope labeling technologies at AstraZeneca through academic-industrial collaboration

Abstract

Keywords

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