Addressable and unidirectional energy transfer along a DNA three-way junction programmed by pyrrole-imidazole polyamides

Wu Su; Clive R. Bagshaw; Glenn A. Burley

doi:10.1038/srep01883

Addressable and unidirectional energy transfer along a DNA three-way junction programmed by pyrrole-imidazole polyamides

Wu Su, Clive R. Bagshaw, Glenn A. Burley

Pure And Applied Chemistry

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16 Citations (Scopus)

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Abstract

We describe a photonic waveguide where FRET is routed uni-directionally along a double-stranded DNA track. The efficiency of FRET is modulated by the supramolecular control of fluorophores along double-stranded DNA using fluorophore-tethered Pyrrole-Imidazole polyamides (PAs). We show that uni-directional FRET is enhanced by the complete assembly of each of the constituent parts, resulting in the selective routing of light along simple DNA duplexes as well as a three-way junction (3WJ).

Original language	English
Article number	1883
Number of pages	6
Journal	Scientific Reports
Volume	3
DOIs	https://doi.org/10.1038/srep01883
Publication status	Published - 24 May 2013

Keywords

ninding
nanotechnology
hairpin polyamide
photonic wires
origami
arrays
proteins
minor-grrove

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10.1038/srep01883

SuBagshawBurley_ScientificReports2013Final published version, 1.45 MBLicence: CC BY 4.0

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AB - We describe a photonic waveguide where FRET is routed uni-directionally along a double-stranded DNA track. The efficiency of FRET is modulated by the supramolecular control of fluorophores along double-stranded DNA using fluorophore-tethered Pyrrole-Imidazole polyamides (PAs). We show that uni-directional FRET is enhanced by the complete assembly of each of the constituent parts, resulting in the selective routing of light along simple DNA duplexes as well as a three-way junction (3WJ).

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KW - nanotechnology

KW - hairpin polyamide

KW - photonic wires

KW - origami

KW - arrays

KW - proteins

KW - minor-grrove

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ER -

Addressable and unidirectional energy transfer along a DNA three-way junction programmed by pyrrole-imidazole polyamides

Abstract

Keywords

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New Molecular Tools For The 21st Century: Molecular Design Of New DNA-Based Devices

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Addressable and unidirectional energy transfer along a DNA three-way junction programmed by pyrrole-imidazole polyamides

Abstract

Keywords

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New Molecular Tools For The 21st Century: Molecular Design Of New DNA-Based Devices

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