Acute respiratory-failure and CNS-depressing drugs

J.M.B. Gray, B. Paice, F. Moran, D.A. Henry, G. Gettinby, D.H. Lawson

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


Data from a drug surveillance programme were analysed to estimate the frequency with which patients with a diagnosis of respiratory failure had been exposed to CNS-depressing drugs. Eleven out of 37 patients with respiratory failure had received such medication. A detailed comparison of these patients and controls admitted to hospital because of respiratory disease who did not develop respiratory failure failed to reveal significant differences in drug usage. This unexpected finding suggests that patients with respiratory disease of equal severity may vary greatly in their tendency to develop carbon dioxide retention following administration of drugs with respiratory depressant properties.
Original languageEnglish
Pages (from-to)279-282
Number of pages3
JournalPostgraduate Medical Journal
Issue number667
Publication statusPublished - 1981


  • acute respiratory-failure
  • CNS-depressing drugs


Dive into the research topics of 'Acute respiratory-failure and CNS-depressing drugs'. Together they form a unique fingerprint.

Cite this