TY - JOUR
T1 - ActinoBase
T2 - tools and protocols for researchers working on Streptomyces and other filamentous actinobacteria
AU - Feeney, Morgan Anne
AU - Newitt, Jake Terry
AU - Addington, Emily
AU - Algora-Gallardo, Lis
AU - Allan, Craig
AU - Balis, Lucas
AU - Birke, Anna S.
AU - Castaño-Espriu, Laia
AU - Charkoudian, Louise K.
AU - Devine, Rebecca
AU - Gayrard, Damien
AU - Hamilton, Jacob
AU - Hennrich, Oliver
AU - Hoskisson, Paul A.
AU - Keith-Baker, Molly
AU - Klein, Joshua G.
AU - Kruasuwan, Worarat
AU - Mark, David R.
AU - Mast, Yvonne
AU - McHugh, Rebecca E.
AU - McLean, Thomas C.
AU - Mohit, Elmira
AU - Munnoch, John T.
AU - Murray, Jordan
AU - Noble, Katie
AU - Otani, Hiroshi
AU - Parra, Jonathan
AU - Pereira, Camila F.
AU - Perry, Louisa
AU - Pintor-Escobar, Linamaria
AU - Pritchard, Leighton
AU - Prudence, Samuel M. M.
AU - Russell, Alicia H.
AU - Schniete, Jana K.
AU - Seipke, Ryan F.
AU - Sélem-Mojica, Nelly
AU - Undabarrena, Agustina
AU - Vind, Kristiina
AU - van Wezel, Gilles P.
AU - Wilkinson, Barrie
AU - Worsley, Sarah F.
AU - Duncan, Katherine R.
AU - Fernández-Martínez, Lorena T.
AU - Hutchings, Matthew I.
PY - 2022/7/1
Y1 - 2022/7/1
N2 - Actinobacteria is an ancient phylum of Gram-positive bacteria with a characteristic high GC content to their DNA. The ActinoBase Wiki is focused on the filamentous actinobacteria, such as Streptomyces species, and the techniques and growth conditions used to study them. These organisms are studied because of their complex developmental life cycles and diverse specialised metabolism which produces many of the antibiotics currently used in the clinic. ActinoBase is a community effort that provides valuable and freely accessible resources, including protocols and practical information about filamentous actinobacteria. It is aimed at enabling knowledge exchange between members of the international research community working with these fascinating bacteria. Actin-oBase is an anchor platform that underpins worldwide efforts to understand the ecology, biology and metabolic potential of these organisms. There are two key differences that set ActinoBase apart from other Wiki-based platforms: [1] ActinoBase is specifically aimed at researchers working on filamentous actinobacteria and is tailored to help users overcome challenges working with these bacteria and [2] it provides a freely accessible resource with global networking opportunities for researchers with a broad range of experience in this field.
AB - Actinobacteria is an ancient phylum of Gram-positive bacteria with a characteristic high GC content to their DNA. The ActinoBase Wiki is focused on the filamentous actinobacteria, such as Streptomyces species, and the techniques and growth conditions used to study them. These organisms are studied because of their complex developmental life cycles and diverse specialised metabolism which produces many of the antibiotics currently used in the clinic. ActinoBase is a community effort that provides valuable and freely accessible resources, including protocols and practical information about filamentous actinobacteria. It is aimed at enabling knowledge exchange between members of the international research community working with these fascinating bacteria. Actin-oBase is an anchor platform that underpins worldwide efforts to understand the ecology, biology and metabolic potential of these organisms. There are two key differences that set ActinoBase apart from other Wiki-based platforms: [1] ActinoBase is specifically aimed at researchers working on filamentous actinobacteria and is tailored to help users overcome challenges working with these bacteria and [2] it provides a freely accessible resource with global networking opportunities for researchers with a broad range of experience in this field.
KW - actinobacteria
KW - antibiotics
KW - BGCs
KW - CRISPR
KW - specialised metabolites
KW - Streptomyces
U2 - 10.1099/mgen.0.000824
DO - 10.1099/mgen.0.000824
M3 - Article
VL - 8
JO - Microbial Genomics
JF - Microbial Genomics
SN - 2057-5858
IS - 7
M1 - 000824
ER -