A systematic study on the self-assembly behaviour of multi component fmoc-amino acid-poly(oxazoline) systems

Pier-Francesco Caponi, Rein V. Ulijn

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

We report a systematic study of a modular approach to create multi-component supramolecular nanostructures that can be tailored to be both enzyme and temperature responsive. Using a straightforward synthetic approach we functionalised a thermal responsive polymer, poly(2-isopropyl-2-oxazoline), with fluorenylmethoxycarbonyl-amino acids that drive the self-assembly. Depending on the properties of appended amino acids, these polymers undergo substantial morphological changes in response to the catalytic action of alkaline phosphatase.

LanguageEnglish
Pages1399-1415
Number of pages17
JournalPolymers
Volume4
Issue number3
Early online date24 Jul 2012
DOIs
Publication statusPublished - 30 Sep 2012

Fingerprint

Self assembly
Amino acids
Polymers
polymer
amino acid
Amino Acids
Nanostructures
Phosphatases
phosphatase
Alkaline Phosphatase
Enzymes
Hot Temperature
enzyme
Temperature
temperature
poly(2-isopropyl-2-oxazoline)

Keywords

  • responsive polymers
  • amino acids
  • enzyme responsive materials
  • modular approach
  • multi-component
  • supramolecular nanostructures
  • thermal responsive polymer,
  • fluorenylmethoxycarbonyl-amino acids

Cite this

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A systematic study on the self-assembly behaviour of multi component fmoc-amino acid-poly(oxazoline) systems. / Caponi, Pier-Francesco; Ulijn, Rein V.

In: Polymers, Vol. 4, No. 3, 30.09.2012, p. 1399-1415.

Research output: Contribution to journalArticle

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