A stereodivergent asymmetric approach to difluorinated aldonic acids

Christophe Audouard, Igor Barsukov, John Fawcett, Gerry A Griffith, Jonathan Percy, Stephane Pintat, Clive A Smith

Research output: Contribution to journalArticle

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105 Downloads (Pure)

Abstract

A (bromodifluoromethyl)alkyne has been deployed in a stereoselective route to difluorinated aldonic acid analogues, in which a Sharpless asymmetric dihydroxylation reaction and diastereoisomer separation set the stage for phenyl group oxidation.
Original languageEnglish
Pages (from-to)1526-1527
Number of pages2
JournalChemical Communications
Issue number13
DOIs
Publication statusPublished - 2004

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Alkynes
Oxidation
Acids

Keywords

  • difluorinated aldonic acid
  • asymmetric dihydroxylation reaction
  • phenyl group oxidation
  • diastereoisomer separation

Cite this

Audouard, C., Barsukov, I., Fawcett, J., Griffith, G. A., Percy, J., Pintat, S., & Smith, C. A. (2004). A stereodivergent asymmetric approach to difluorinated aldonic acids. Chemical Communications, (13), 1526-1527 . https://doi.org/10.1039/B405067C
Audouard, Christophe ; Barsukov, Igor ; Fawcett, John ; Griffith, Gerry A ; Percy, Jonathan ; Pintat, Stephane ; Smith, Clive A. / A stereodivergent asymmetric approach to difluorinated aldonic acids. In: Chemical Communications. 2004 ; No. 13. pp. 1526-1527 .
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keywords = "difluorinated aldonic acid, asymmetric dihydroxylation reaction , phenyl group oxidation, diastereoisomer separation",
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Audouard, C, Barsukov, I, Fawcett, J, Griffith, GA, Percy, J, Pintat, S & Smith, CA 2004, 'A stereodivergent asymmetric approach to difluorinated aldonic acids', Chemical Communications, no. 13, pp. 1526-1527 . https://doi.org/10.1039/B405067C

A stereodivergent asymmetric approach to difluorinated aldonic acids. / Audouard, Christophe; Barsukov, Igor; Fawcett, John; Griffith, Gerry A; Percy, Jonathan; Pintat, Stephane; Smith, Clive A.

In: Chemical Communications, No. 13, 2004, p. 1526-1527 .

Research output: Contribution to journalArticle

TY - JOUR

T1 - A stereodivergent asymmetric approach to difluorinated aldonic acids

AU - Audouard, Christophe

AU - Barsukov, Igor

AU - Fawcett, John

AU - Griffith, Gerry A

AU - Percy, Jonathan

AU - Pintat, Stephane

AU - Smith, Clive A

PY - 2004

Y1 - 2004

N2 - A (bromodifluoromethyl)alkyne has been deployed in a stereoselective route to difluorinated aldonic acid analogues, in which a Sharpless asymmetric dihydroxylation reaction and diastereoisomer separation set the stage for phenyl group oxidation.

AB - A (bromodifluoromethyl)alkyne has been deployed in a stereoselective route to difluorinated aldonic acid analogues, in which a Sharpless asymmetric dihydroxylation reaction and diastereoisomer separation set the stage for phenyl group oxidation.

KW - difluorinated aldonic acid

KW - asymmetric dihydroxylation reaction

KW - phenyl group oxidation

KW - diastereoisomer separation

U2 - 10.1039/B405067C

DO - 10.1039/B405067C

M3 - Article

SP - 1526

EP - 1527

JO - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

IS - 13

ER -

Audouard C, Barsukov I, Fawcett J, Griffith GA, Percy J, Pintat S et al. A stereodivergent asymmetric approach to difluorinated aldonic acids. Chemical Communications. 2004;(13):1526-1527 . https://doi.org/10.1039/B405067C