A special issue of Essays in Biochemistry on structural mass spectrometry

Hannah M. Britt, Rebecca Beveridge, Antonio N. Calabrese

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Mass spectrometry (MS) is now established as an analytical tool to interrogate the structure and dynamics of proteins and their assemblies. An array of MS-based technologies has been developed, with each providing unique information pertaining to protein structure, and forming the heart of integrative structural biology studies. This special issue includes a collection of review articles that discuss both established and emerging structural MS methodologies, along with examples of how these technologies are being deployed to interrogate protein structure and function. Combined, this collection highlights the immense potential of the structural MS toolkit in the study of molecular mechanisms underpinning cellular homeostasis and disease.
Original languageEnglish
Pages (from-to)147-149
Number of pages3
JournalEssays in Biochemistry
Issue number2
Early online date29 Mar 2023
Publication statusPublished - 29 Mar 2023


  • mass spectrometry (MS)
  • structural proteomics methods
  • biochemistry


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