A simulation model to assess herd-level intervention strategies against E-coli 0157

J.C. Wood, Iain J. McKendrick, George Gettinby

Research output: Contribution to journalArticle

Abstract

A simulation model of a herd of grazing cattle, which has been developed to provide insight into the infection dynamics of E. coli O157 is described. The spatially explicit model enables the modelling of the infection transmission processes to be realistically addressed under field management conditions. The model is used to explore the efficacy of various potential control strategies in reducing the levels of within-herd infection. These measures include restricting the size of herds, niche engineering, improving housing hygiene and vaccination. While a vaccination strategy remains a hypothetical option, it has the potential to be particularly effective. It is likely that the most successful strategy will involve the implementation of a combination of measures.
LanguageEnglish
Pages749-764
Number of pages16
JournalEpidemiology and Infection
Volume135
Issue number5
Early online date17 Nov 2006
DOIs
Publication statusPublished - 2007

Fingerprint

Vaccination
Escherichia coli
Infectious Disease Transmission
Escherichia coli O157
Infection
Hygiene

Keywords

  • simulation model
  • cattle
  • epidemiology
  • infection

Cite this

Wood, J.C. ; McKendrick, Iain J. ; Gettinby, George. / A simulation model to assess herd-level intervention strategies against E-coli 0157. In: Epidemiology and Infection. 2007 ; Vol. 135, No. 5. pp. 749-764.
@article{d722bdbd87684b1a997df4420e9cad7e,
title = "A simulation model to assess herd-level intervention strategies against E-coli 0157",
abstract = "A simulation model of a herd of grazing cattle, which has been developed to provide insight into the infection dynamics of E. coli O157 is described. The spatially explicit model enables the modelling of the infection transmission processes to be realistically addressed under field management conditions. The model is used to explore the efficacy of various potential control strategies in reducing the levels of within-herd infection. These measures include restricting the size of herds, niche engineering, improving housing hygiene and vaccination. While a vaccination strategy remains a hypothetical option, it has the potential to be particularly effective. It is likely that the most successful strategy will involve the implementation of a combination of measures.",
keywords = "simulation model, cattle, epidemiology, infection",
author = "J.C. Wood and McKendrick, {Iain J.} and George Gettinby",
year = "2007",
doi = "10.1017/S0950268806007436.",
language = "English",
volume = "135",
pages = "749--764",
journal = "Epidemiology and Infection",
issn = "0950-2688",
number = "5",

}

A simulation model to assess herd-level intervention strategies against E-coli 0157. / Wood, J.C.; McKendrick, Iain J.; Gettinby, George.

In: Epidemiology and Infection, Vol. 135, No. 5, 2007, p. 749-764.

Research output: Contribution to journalArticle

TY - JOUR

T1 - A simulation model to assess herd-level intervention strategies against E-coli 0157

AU - Wood, J.C.

AU - McKendrick, Iain J.

AU - Gettinby, George

PY - 2007

Y1 - 2007

N2 - A simulation model of a herd of grazing cattle, which has been developed to provide insight into the infection dynamics of E. coli O157 is described. The spatially explicit model enables the modelling of the infection transmission processes to be realistically addressed under field management conditions. The model is used to explore the efficacy of various potential control strategies in reducing the levels of within-herd infection. These measures include restricting the size of herds, niche engineering, improving housing hygiene and vaccination. While a vaccination strategy remains a hypothetical option, it has the potential to be particularly effective. It is likely that the most successful strategy will involve the implementation of a combination of measures.

AB - A simulation model of a herd of grazing cattle, which has been developed to provide insight into the infection dynamics of E. coli O157 is described. The spatially explicit model enables the modelling of the infection transmission processes to be realistically addressed under field management conditions. The model is used to explore the efficacy of various potential control strategies in reducing the levels of within-herd infection. These measures include restricting the size of herds, niche engineering, improving housing hygiene and vaccination. While a vaccination strategy remains a hypothetical option, it has the potential to be particularly effective. It is likely that the most successful strategy will involve the implementation of a combination of measures.

KW - simulation model

KW - cattle

KW - epidemiology

KW - infection

U2 - 10.1017/S0950268806007436.

DO - 10.1017/S0950268806007436.

M3 - Article

VL - 135

SP - 749

EP - 764

JO - Epidemiology and Infection

T2 - Epidemiology and Infection

JF - Epidemiology and Infection

SN - 0950-2688

IS - 5

ER -