Abstract
The synthesis of a series of di-, tri-, and tetrasubstituted non-sym. ureas is described. Di- and trisubstituted ureas are prepd. in excellent yield by treatment of a Ph carbamate in a self-tunable single-mode microwave synthesizer with a primary or secondary amine. The synthetically more challenging tetrasubstituted urea can be prepd. using the 4-nitrophenyl carbamate and a secondary amine.
| Original language | Undefined/Unknown |
|---|---|
| Pages (from-to) | 243-246 |
| Number of pages | 4 |
| Journal | Synlett |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2006 |
Keywords
- urea
- carbamate
- microwave-assisted synthesis
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