A mild, efficient and general method for the chemospecific α-oxygenation of aldehydes is described. Treatment of a series of aldehydes with N-tert-butyl-O-benzoyl hydroxylamine hydrochloride gives the corresponding α-oxygenated carbonyl via a proposed pericyclic rearrangement process.
Beshara, C. S., Hall, A., Jenkins, R. L., Jones, T. C., Parry, R. T., Thomas, S. P., & Tomkinson, N. C. O. (2005). A simple method for the α-oxygenation of aldehydes. Chemical Communications, (11), 1478-1480. https://doi.org/10.1039/b418101h