A radical based addition-elimination route for the preparation of indoles

J.A. Murphy, K.A. Scott, R.S. Sinclair, C.G. Martin, A.R. Kennedy, N. Lewis

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30 Citations (Scopus)

Abstract

Indoles, including tricyclic derivatives, are produced by cyclisations of aryl radicals onto vinyl halides followed by elimination of halide radical and tautomerism of the resulting product; the aryl radicals are produced using clean methodology either by reaction of iodide ions with arenediazonium salts or by reaction of phosphorus-centred radicals with aryl iodides.
Original languageEnglish
Pages (from-to)2395-2408
Number of pages13
JournalJournal of the Chemical Society, Perkin Transactions 1
Volume2000
Issue number15
DOIs
Publication statusPublished - 10 Jul 2000

Keywords

  • Indoles
  • tricyclic derivatives
  • aryl radicals
  • iodide ions
  • arenediazonium

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