Indoles, including tricyclic derivatives, are produced by cyclisations of aryl radicals onto vinyl halides followed by elimination of halide radical and tautomerism of the resulting product; the aryl radicals are produced using clean methodology either by reaction of iodide ions with arenediazonium salts or by reaction of phosphorus-centred radicals with aryl iodides.
|Number of pages||13|
|Journal||Journal of the Chemical Society, Perkin Transactions 1|
|Publication status||Published - 10 Jul 2000|
- tricyclic derivatives
- aryl radicals
- iodide ions
Murphy, J. A., Scott, K. A., Sinclair, R. S., Martin, C. G., Kennedy, A. R., & Lewis, N. (2000). A radical based addition-elimination route for the preparation of indoles. Journal of the Chemical Society, Perkin Transactions 1, 2000(15), 2395-2408. https://doi.org/10.1039/b002565h