A radical based addition-elimination route for the preparation of indoles

J.A. Murphy, K.A. Scott, R.S. Sinclair, C.G. Martin, A.R. Kennedy, N. Lewis

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Indoles, including tricyclic derivatives, are produced by cyclisations of aryl radicals onto vinyl halides followed by elimination of halide radical and tautomerism of the resulting product; the aryl radicals are produced using clean methodology either by reaction of iodide ions with arenediazonium salts or by reaction of phosphorus-centred radicals with aryl iodides.
LanguageEnglish
Pages2395-2408
Number of pages13
JournalJournal of the Chemical Society, Perkin Transactions 1
Volume2000
Issue number15
DOIs
Publication statusPublished - 10 Jul 2000

Fingerprint

Indoles
Iodides
Cyclization
Phosphorus
Salts
Ions
Derivatives

Keywords

  • Indoles
  • tricyclic derivatives
  • aryl radicals
  • iodide ions
  • arenediazonium

Cite this

Murphy, J.A. ; Scott, K.A. ; Sinclair, R.S. ; Martin, C.G. ; Kennedy, A.R. ; Lewis, N. / A radical based addition-elimination route for the preparation of indoles. In: Journal of the Chemical Society, Perkin Transactions 1. 2000 ; Vol. 2000, No. 15. pp. 2395-2408.
@article{d074273a0a984663a94334f91c6dee87,
title = "A radical based addition-elimination route for the preparation of indoles",
abstract = "Indoles, including tricyclic derivatives, are produced by cyclisations of aryl radicals onto vinyl halides followed by elimination of halide radical and tautomerism of the resulting product; the aryl radicals are produced using clean methodology either by reaction of iodide ions with arenediazonium salts or by reaction of phosphorus-centred radicals with aryl iodides.",
keywords = "Indoles, tricyclic derivatives, aryl radicals, iodide ions, arenediazonium",
author = "J.A. Murphy and K.A. Scott and R.S. Sinclair and C.G. Martin and A.R. Kennedy and N. Lewis",
year = "2000",
month = "7",
day = "10",
doi = "10.1039/b002565h",
language = "English",
volume = "2000",
pages = "2395--2408",
journal = "Journal of the Chemical Society, Perkin Transactions 1",
issn = "1472-7781",
number = "15",

}

A radical based addition-elimination route for the preparation of indoles. / Murphy, J.A.; Scott, K.A.; Sinclair, R.S.; Martin, C.G.; Kennedy, A.R.; Lewis, N.

In: Journal of the Chemical Society, Perkin Transactions 1, Vol. 2000, No. 15, 10.07.2000, p. 2395-2408.

Research output: Contribution to journalArticle

TY - JOUR

T1 - A radical based addition-elimination route for the preparation of indoles

AU - Murphy, J.A.

AU - Scott, K.A.

AU - Sinclair, R.S.

AU - Martin, C.G.

AU - Kennedy, A.R.

AU - Lewis, N.

PY - 2000/7/10

Y1 - 2000/7/10

N2 - Indoles, including tricyclic derivatives, are produced by cyclisations of aryl radicals onto vinyl halides followed by elimination of halide radical and tautomerism of the resulting product; the aryl radicals are produced using clean methodology either by reaction of iodide ions with arenediazonium salts or by reaction of phosphorus-centred radicals with aryl iodides.

AB - Indoles, including tricyclic derivatives, are produced by cyclisations of aryl radicals onto vinyl halides followed by elimination of halide radical and tautomerism of the resulting product; the aryl radicals are produced using clean methodology either by reaction of iodide ions with arenediazonium salts or by reaction of phosphorus-centred radicals with aryl iodides.

KW - Indoles

KW - tricyclic derivatives

KW - aryl radicals

KW - iodide ions

KW - arenediazonium

UR - http://dx.doi.org/10.1039/b002565h

U2 - 10.1039/b002565h

DO - 10.1039/b002565h

M3 - Article

VL - 2000

SP - 2395

EP - 2408

JO - Journal of the Chemical Society, Perkin Transactions 1

T2 - Journal of the Chemical Society, Perkin Transactions 1

JF - Journal of the Chemical Society, Perkin Transactions 1

SN - 1472-7781

IS - 15

ER -