A portable infrared spectrometer for in-vivo measurements of limb oxygenation

Giovanni G. Guizzetti, Mario Giardini, Matteo Bavera, Paolo Lago, Mario Corti, Colomba Falcone

Research output: Contribution to conferencePoster

Abstract

Near Infrared Spectroscopy (NIRS) can be employed to noninvasively and continuously measure in-vivo local changes in haemodynamics and oxygenation of human tissues. To this respect, the availability of a portable NIRS spectrometer would be highly desirable, as it could be of major interest for the monitoring of peripheral vascular diseases during unattended patient activities. We present a portable NIRS acquisition system prototype, which can be employed during unattended exercise or everyday life. The prototype is able to control four LED sources and a detector. Such a number of sources is theoretically sufficient for multi-wavelength spectroscopy of tissue constituents other than oxygen, such as cytochrome aa3. The LEDs and the detector are carried by separate probes, which carry also the relevant miniaturized drivers and preamplifiers. The probes can be non-invasively attached to the patient. A single-chip mixed-signal RISC microcontroller performs all the data sampling and acquisition functions using either a time-multiplexing scheme or a digital correlation technique. The acquired data are stored on an on-board 64 Kb EEPROM bank that allows for a few hours of continuous recording. The recorded signals can be subsequently uploaded to a handheld data logger or to a personal computer for storage, visualization and postanalysis. The resulting instrument is compact and lightweight. The probes are sufficiently small to avoid hindrance to movement and exercise. A test of the instrument performance during everyday activities is presented and discussed.
LanguageEnglish
Publication statusPublished - 13 Jun 2000
EventINFMeeting 2000 - Genova, Italy
Duration: 12 Jun 200016 Jun 2000

Conference

ConferenceINFMeeting 2000
CountryItaly
CityGenova
Period12/06/0016/06/00

Fingerprint

Infrared spectrometers
Near infrared spectroscopy
Oxygenation
Light emitting diodes
Tissue
Detectors
Reduced instruction set computing
Hemodynamics
Electron Transport Complex IV
Microcontrollers
Multiplexing
Personal computers
Light sources
Spectrometers
Visualization
Availability
Spectroscopy
Oxygen
Sampling
Wavelength

Cite this

Guizzetti, G. G., Giardini, M., Bavera, M., Lago, P., Corti, M., & Falcone, C. (2000). A portable infrared spectrometer for in-vivo measurements of limb oxygenation. Poster session presented at INFMeeting 2000, Genova, Italy.
Guizzetti, Giovanni G. ; Giardini, Mario ; Bavera, Matteo ; Lago, Paolo ; Corti, Mario ; Falcone, Colomba. / A portable infrared spectrometer for in-vivo measurements of limb oxygenation. Poster session presented at INFMeeting 2000, Genova, Italy.
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Guizzetti, GG, Giardini, M, Bavera, M, Lago, P, Corti, M & Falcone, C 2000, 'A portable infrared spectrometer for in-vivo measurements of limb oxygenation' INFMeeting 2000, Genova, Italy, 12/06/00 - 16/06/00, .

A portable infrared spectrometer for in-vivo measurements of limb oxygenation. / Guizzetti, Giovanni G.; Giardini, Mario; Bavera, Matteo; Lago, Paolo; Corti, Mario; Falcone, Colomba.

2000. Poster session presented at INFMeeting 2000, Genova, Italy.

Research output: Contribution to conferencePoster

TY - CONF

T1 - A portable infrared spectrometer for in-vivo measurements of limb oxygenation

AU - Guizzetti, Giovanni G.

AU - Giardini, Mario

AU - Bavera, Matteo

AU - Lago, Paolo

AU - Corti, Mario

AU - Falcone, Colomba

PY - 2000/6/13

Y1 - 2000/6/13

N2 - Near Infrared Spectroscopy (NIRS) can be employed to noninvasively and continuously measure in-vivo local changes in haemodynamics and oxygenation of human tissues. To this respect, the availability of a portable NIRS spectrometer would be highly desirable, as it could be of major interest for the monitoring of peripheral vascular diseases during unattended patient activities. We present a portable NIRS acquisition system prototype, which can be employed during unattended exercise or everyday life. The prototype is able to control four LED sources and a detector. Such a number of sources is theoretically sufficient for multi-wavelength spectroscopy of tissue constituents other than oxygen, such as cytochrome aa3. The LEDs and the detector are carried by separate probes, which carry also the relevant miniaturized drivers and preamplifiers. The probes can be non-invasively attached to the patient. A single-chip mixed-signal RISC microcontroller performs all the data sampling and acquisition functions using either a time-multiplexing scheme or a digital correlation technique. The acquired data are stored on an on-board 64 Kb EEPROM bank that allows for a few hours of continuous recording. The recorded signals can be subsequently uploaded to a handheld data logger or to a personal computer for storage, visualization and postanalysis. The resulting instrument is compact and lightweight. The probes are sufficiently small to avoid hindrance to movement and exercise. A test of the instrument performance during everyday activities is presented and discussed.

AB - Near Infrared Spectroscopy (NIRS) can be employed to noninvasively and continuously measure in-vivo local changes in haemodynamics and oxygenation of human tissues. To this respect, the availability of a portable NIRS spectrometer would be highly desirable, as it could be of major interest for the monitoring of peripheral vascular diseases during unattended patient activities. We present a portable NIRS acquisition system prototype, which can be employed during unattended exercise or everyday life. The prototype is able to control four LED sources and a detector. Such a number of sources is theoretically sufficient for multi-wavelength spectroscopy of tissue constituents other than oxygen, such as cytochrome aa3. The LEDs and the detector are carried by separate probes, which carry also the relevant miniaturized drivers and preamplifiers. The probes can be non-invasively attached to the patient. A single-chip mixed-signal RISC microcontroller performs all the data sampling and acquisition functions using either a time-multiplexing scheme or a digital correlation technique. The acquired data are stored on an on-board 64 Kb EEPROM bank that allows for a few hours of continuous recording. The recorded signals can be subsequently uploaded to a handheld data logger or to a personal computer for storage, visualization and postanalysis. The resulting instrument is compact and lightweight. The probes are sufficiently small to avoid hindrance to movement and exercise. A test of the instrument performance during everyday activities is presented and discussed.

M3 - Poster

ER -

Guizzetti GG, Giardini M, Bavera M, Lago P, Corti M, Falcone C. A portable infrared spectrometer for in-vivo measurements of limb oxygenation. 2000. Poster session presented at INFMeeting 2000, Genova, Italy.