A parallel group randomised open blinded evaluation of acceptance and commitment therapy for depression after psychosis: a pilot trial protocol (ADAPT)

Andrew Gumley, Ross White, Andy Briggs, Ian Ford, Sarah Barry, Corinna Stewart, Sara Beedie, Caoimhe Clarke, Rachel Macleod, Emma Lidstone, Hamish McLeod

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: Depression is one of the major contributors to poorer quality of life among individuals with psychosis and schizophrenia. Aims: This study protocol was designed as a pilot trial to determine the parameters of a larger, definitive pragmatic multi-centre randomised controlled trial of Acceptance and Commitment Therapy for depression after psychosis (ACTdp) for individuals with a diagnosis of schizophrenia who also meet diagnostic criteria for major depression. Methods: The study protocol was registered before initiating recruitment and was designed as a Parallel-group Randomised Open Blinded Evaluation (PROBE) comparing ACTdp plus standard care (SC) or SC alone. Participants were required to meet DSM-IV-TR criteria for schizophrenia and major depression (confirmed by Structured Clinical Interview for DSM/SCID-I and Calgary Depression Scale for Schizophrenia; score gt; 7). Blinded follow-ups are undertaken at 5 months (end of treatment) and at 10 months (5 months post treatment). Implications: The pilot aims to establish the basis for a larger-scale multi-centre randomised controlled trial of ACTdp. The most important study outcomes that will provide the basis of informing progression to a full trial are identified a priori as Population, Intervention, Control and Outcomes (PICO).
LanguageEnglish
Pages143-155
Number of pages13
JournalPsychosis
Volume8
Issue number2
Early online date28 Oct 2015
DOIs
Publication statusPublished - 2016

Fingerprint

Acceptance and Commitment Therapy
Clinical Protocols
Psychotic Disorders
Therapy
Depression
Evaluation
Schizophrenia
Randomized Controlled Trial
Randomized Controlled Trials
Population Control
Quality of Life
Standard of Care
Commitment
Progression
Diagnostic and Statistical Manual of Mental Disorders
Diagnostics
Outcome Assessment (Health Care)
Interviews

Keywords

  • schizophrenia
  • depression
  • randomised controlled trial
  • pilot
  • acceptanc and commitment therapy

Cite this

Gumley, Andrew ; White, Ross ; Briggs, Andy ; Ford, Ian ; Barry, Sarah ; Stewart, Corinna ; Beedie, Sara ; Clarke, Caoimhe ; Macleod, Rachel ; Lidstone, Emma ; McLeod, Hamish. / A parallel group randomised open blinded evaluation of acceptance and commitment therapy for depression after psychosis : a pilot trial protocol (ADAPT). 2016 ; Vol. 8, No. 2. pp. 143-155.
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Gumley, A, White, R, Briggs, A, Ford, I, Barry, S, Stewart, C, Beedie, S, Clarke, C, Macleod, R, Lidstone, E & McLeod, H 2016, 'A parallel group randomised open blinded evaluation of acceptance and commitment therapy for depression after psychosis: a pilot trial protocol (ADAPT)' vol. 8, no. 2, pp. 143-155. https://doi.org/10.1080/17522439.2015.1100669

A parallel group randomised open blinded evaluation of acceptance and commitment therapy for depression after psychosis : a pilot trial protocol (ADAPT). / Gumley, Andrew; White, Ross; Briggs, Andy; Ford, Ian; Barry, Sarah; Stewart, Corinna; Beedie, Sara; Clarke, Caoimhe; Macleod, Rachel; Lidstone, Emma; McLeod, Hamish.

Vol. 8, No. 2, 2016, p. 143-155.

Research output: Contribution to journalArticle

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AU - White, Ross

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AU - Ford, Ian

AU - Barry, Sarah

AU - Stewart, Corinna

AU - Beedie, Sara

AU - Clarke, Caoimhe

AU - Macleod, Rachel

AU - Lidstone, Emma

AU - McLeod, Hamish

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