A paracetamol-morpholine adduct

I D H Oswald, W D S Motherwell, S Parsons, C R Pulham

Research output: Contribution to journalArticle

Abstract

Paracetamol [also known as acetaminophen or N-(4-hydroxyphenyl) acetamide] is an important analgesic drug that has recently been cocrystallized with a series of cyclic N- and Odonor compounds. This paper describes the formation of a
paracetamol adduct with morpholine, viz. paracetamol± morpholine (1/2.5), C8H9NO22.5C4H9NO. There are ®ve morpholine molecules and two paracetamol molecules in the unit cell. The paracetamol molecules are held together by
hydrogen bonding via morpholine molecules, one of which is disordered about an inversion centre.
LanguageEnglish
PagesO1290-O1292
Number of pages3
JournalActa Crystallographica Section E: Structure Reports
Volume58
Issue numberPart 11
Early online date15 Oct 2002
DOIs
Publication statusPublished - Nov 2002

Fingerprint

Acetaminophen
adducts
Molecules
molecules
drugs
inversions
Analgesics
morpholine
cells

Keywords

  • crystals
  • acetaminophen
  • N-(4-hydroxyphenyl)acetamide
  • cocrystallized
  • paracetamol

Cite this

Oswald, I D H ; Motherwell, W D S ; Parsons, S ; Pulham, C R . / A paracetamol-morpholine adduct. In: Acta Crystallographica Section E: Structure Reports. 2002 ; Vol. 58, No. Part 11. pp. O1290-O1292.
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Oswald, IDH, Motherwell, WDS, Parsons, S & Pulham, CR 2002, 'A paracetamol-morpholine adduct' Acta Crystallographica Section E: Structure Reports, vol. 58, no. Part 11, pp. O1290-O1292. https://doi.org/10.1107/S1600536802018111

A paracetamol-morpholine adduct. / Oswald, I D H ; Motherwell, W D S ; Parsons, S ; Pulham, C R .

In: Acta Crystallographica Section E: Structure Reports, Vol. 58, No. Part 11, 11.2002, p. O1290-O1292.

Research output: Contribution to journalArticle

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AU - Oswald, I D H

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AU - Parsons, S

AU - Pulham, C R

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KW - crystals

KW - acetaminophen

KW - N-(4-hydroxyphenyl)acetamide

KW - cocrystallized

KW - paracetamol

U2 - 10.1107/S1600536802018111

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