Projects per year
Abstract
2,5-Diaryltetrazoles are a diverse range of compounds of considerable interest within the field of photochemistry as a valuable precursor of the nitrile imine 1,3-dipole. Current literature approaches toward this heterocycle remain unsuitable for the practical synthesis of a library of these derivatives. Herein, we disclose the development of a modular approach toward 2,5-diaryltetrazoles compatible with an array-type protocol, facilitated by a tandem Suzuki-hydrogenolysis approach.
| Original language | English |
|---|---|
| Pages (from-to) | 7413-7423 |
| Number of pages | 11 |
| Journal | Journal of Organic Chemistry |
| Volume | 85 |
| Issue number | 11 |
| Early online date | 21 May 2020 |
| DOIs | |
| Publication status | E-pub ahead of print - 21 May 2020 |
Keywords
- 2,5-diaryltetrazoles
- photochemistry
- modular approach
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Projects
- 1 Active
Industrial Case Account 2016 | Livingstone, Keith
Jamieson, C., Tomkinson, N. & Livingstone, K.
EPSRC (Engineering and Physical Sciences Research Council)
1/10/16 → 1/01/21
Project: Research Studentship Case - Internally allocated
Cite this
Livingstone, K., Bertrand, S., & Jamieson, C. (2020). A one-pot Suzuki-hydrogenolysis protocol for the modular synthesis of 2,5-diaryltetrazoles. Journal of Organic Chemistry, 85(11), 7413-7423. https://doi.org/10.1021/acs.joc.0c00807