Many in-vitro systems used during pre-clinical trials fail to recreate the biological complexity of the in-vivo neural microenvironment.Taking advantage of recent advances in microfluidic technology, we seek to develop a perfusion based drug discovery platform that is capable of high-throughput pharmacological profiling. This in turn will allow us to better understand how drugs influence the communication between functionally connected neural networks.
|Publication status||Published - 2 Jul 2016|
|Event||10th FENS (Federation of European Neuroscience Societies) Forum of Neuroscience 2016 - Copenhagen, Denmark|
Duration: 2 Jul 2016 → 6 Jul 2016
Conference number: 10th
|Conference||10th FENS (Federation of European Neuroscience Societies) Forum of Neuroscience 2016|
|Period||2/07/16 → 6/07/16|
- microfluid drug testing
- drug discovery programs
- microfluidic array
MacKerron, C., Robertson, G., Bushell, T., & Zagnoni, M. (2016). A novel microfluidic drug testing platform for studying communication between independent neural networks. Paper presented at 10th FENS (Federation of European Neuroscience Societies) Forum of Neuroscience 2016, Copenhagen, Denmark.