A novel microfluidic drug testing platform for studying communication between independent neural networks

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Abstract

Many in-vitro systems used during pre-clinical trials fail to recreate the biological complexity of the in-vivo neural microenvironment.Taking advantage of recent advances in microfluidic technology, we seek to develop a perfusion based drug discovery platform that is capable of high-throughput pharmacological profiling. This in turn will allow us to better understand how drugs influence the communication between functionally connected neural networks.
Original languageEnglish
Publication statusPublished - 2 Jul 2016
Event10th FENS (Federation of European Neuroscience Societies) Forum of Neuroscience 2016 - Copenhagen, Denmark
Duration: 2 Jul 20166 Jul 2016
Conference number: 10th

Conference

Conference10th FENS (Federation of European Neuroscience Societies) Forum of Neuroscience 2016
CountryDenmark
CityCopenhagen
Period2/07/166/07/16

Keywords

  • microfluid drug testing
  • drug discovery programs
  • microfluidic array

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    MacKerron, C., Robertson, G., Bushell, T., & Zagnoni, M. (2016). A novel microfluidic drug testing platform for studying communication between independent neural networks. Paper presented at 10th FENS (Federation of European Neuroscience Societies) Forum of Neuroscience 2016, Copenhagen, Denmark.