A novel Hemi-Body Irradiation technique using electron beams (HBIe)

Panagiotis Delinikolas, Georgios Patatoukas, Vassilios Kouloulias, Maria Dilvoi, Agapi Plousi, Efstathios Efstathopoulos, Kalliopi Platoni

Research output: Contribution to journalArticle

1 Citation (Scopus)
13 Downloads (Pure)

Abstract

Purpose
Certain radiation responsive skin diseases may develop symptoms on the upper or the lower half of the body. The concept of a novel Hemi-Body Electron Irradiation (HBIe) technique, described in this work, provides a low cost, LINAC based, intermediate treatment option in between extremely localized and Total Skin irradiation techniques.
Materials and methods
The HBIe technique, developed in our department, incorporates a custom crafted treatment chamber equipped with adjustable Pb shielding and a single electron beam in extended Source-Skin Distance (SSD) setup. The patient is positioned in 'Stanford' technique positions. The geometrical setup provides both optimal dose homogeneity and dose deposition up to a depth of 2 cm. To confirm this, the following characteristics were measured and evaluated: a) percentage depth dose (PDD) on the treatment plane produced by a single electron beam at perpendicular incidence for six fields at 'Stanford' angles, b) 2D profile of the entrance dose on the treatment plane produced by a single field and c) the total surface dose on an anthropomorphic phantom delivered by all 6 fields.
Results
The resulting homogeneity of the surface dose in the treatment plane for an average patient was 5–6%, while surface dose homogeneity on the anthropomorphic phantom was 7% for both the upper and the lower HBIe variants. The total PDD exhibits an almost linear decrease to a practical range of 2 g/cm2.
Conclusion
In conclusion, HBIe was proven effective in delivering the prescribed dose to the target area, while protecting the healthy skin.
Original languageEnglish
Pages (from-to)16-24
Number of pages9
JournalPhysica Medica
Volume46
DOIs
Publication statusPublished - 28 Feb 2018

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Electron beams
Skin
Irradiation
electron beams
dosage
irradiation
homogeneity
Electron irradiation
Shielding
Radiation
electron irradiation
Costs
entrances
shielding
incidence
chambers
radiation
profiles

Keywords

  • half-body skin irradiation
  • Stanford technique
  • Kaposi’s sarcoma
  • t-cell lymphoma

Cite this

Delinikolas, P., Patatoukas, G., Kouloulias, V., Dilvoi, M., Plousi, A., Efstathopoulos, E., & Platoni, K. (2018). A novel Hemi-Body Irradiation technique using electron beams (HBIe). Physica Medica, 46, 16-24. https://doi.org/10.1016/j.ejmp.2017.12.022
Delinikolas, Panagiotis ; Patatoukas, Georgios ; Kouloulias, Vassilios ; Dilvoi, Maria ; Plousi, Agapi ; Efstathopoulos, Efstathios ; Platoni, Kalliopi. / A novel Hemi-Body Irradiation technique using electron beams (HBIe). In: Physica Medica. 2018 ; Vol. 46. pp. 16-24.
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title = "A novel Hemi-Body Irradiation technique using electron beams (HBIe−)",
abstract = "PurposeCertain radiation responsive skin diseases may develop symptoms on the upper or the lower half of the body. The concept of a novel Hemi-Body Electron Irradiation (HBIe−) technique, described in this work, provides a low cost, LINAC based, intermediate treatment option in between extremely localized and Total Skin irradiation techniques.Materials and methodsThe HBIe− technique, developed in our department, incorporates a custom crafted treatment chamber equipped with adjustable Pb shielding and a single electron beam in extended Source-Skin Distance (SSD) setup. The patient is positioned in 'Stanford' technique positions. The geometrical setup provides both optimal dose homogeneity and dose deposition up to a depth of 2 cm. To confirm this, the following characteristics were measured and evaluated: a) percentage depth dose (PDD) on the treatment plane produced by a single electron beam at perpendicular incidence for six fields at 'Stanford' angles, b) 2D profile of the entrance dose on the treatment plane produced by a single field and c) the total surface dose on an anthropomorphic phantom delivered by all 6 fields.ResultsThe resulting homogeneity of the surface dose in the treatment plane for an average patient was 5–6{\%}, while surface dose homogeneity on the anthropomorphic phantom was 7{\%} for both the upper and the lower HBIe− variants. The total PDD exhibits an almost linear decrease to a practical range of 2 g/cm2.ConclusionIn conclusion, HBIe− was proven effective in delivering the prescribed dose to the target area, while protecting the healthy skin.",
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author = "Panagiotis Delinikolas and Georgios Patatoukas and Vassilios Kouloulias and Maria Dilvoi and Agapi Plousi and Efstathios Efstathopoulos and Kalliopi Platoni",
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Delinikolas, P, Patatoukas, G, Kouloulias, V, Dilvoi, M, Plousi, A, Efstathopoulos, E & Platoni, K 2018, 'A novel Hemi-Body Irradiation technique using electron beams (HBIe)', Physica Medica, vol. 46, pp. 16-24. https://doi.org/10.1016/j.ejmp.2017.12.022

A novel Hemi-Body Irradiation technique using electron beams (HBIe). / Delinikolas, Panagiotis; Patatoukas, Georgios; Kouloulias, Vassilios; Dilvoi, Maria; Plousi, Agapi; Efstathopoulos, Efstathios; Platoni, Kalliopi.

In: Physica Medica, Vol. 46, 28.02.2018, p. 16-24.

Research output: Contribution to journalArticle

TY - JOUR

T1 - A novel Hemi-Body Irradiation technique using electron beams (HBIe−)

AU - Delinikolas, Panagiotis

AU - Patatoukas, Georgios

AU - Kouloulias, Vassilios

AU - Dilvoi, Maria

AU - Plousi, Agapi

AU - Efstathopoulos, Efstathios

AU - Platoni, Kalliopi

PY - 2018/2/28

Y1 - 2018/2/28

N2 - PurposeCertain radiation responsive skin diseases may develop symptoms on the upper or the lower half of the body. The concept of a novel Hemi-Body Electron Irradiation (HBIe−) technique, described in this work, provides a low cost, LINAC based, intermediate treatment option in between extremely localized and Total Skin irradiation techniques.Materials and methodsThe HBIe− technique, developed in our department, incorporates a custom crafted treatment chamber equipped with adjustable Pb shielding and a single electron beam in extended Source-Skin Distance (SSD) setup. The patient is positioned in 'Stanford' technique positions. The geometrical setup provides both optimal dose homogeneity and dose deposition up to a depth of 2 cm. To confirm this, the following characteristics were measured and evaluated: a) percentage depth dose (PDD) on the treatment plane produced by a single electron beam at perpendicular incidence for six fields at 'Stanford' angles, b) 2D profile of the entrance dose on the treatment plane produced by a single field and c) the total surface dose on an anthropomorphic phantom delivered by all 6 fields.ResultsThe resulting homogeneity of the surface dose in the treatment plane for an average patient was 5–6%, while surface dose homogeneity on the anthropomorphic phantom was 7% for both the upper and the lower HBIe− variants. The total PDD exhibits an almost linear decrease to a practical range of 2 g/cm2.ConclusionIn conclusion, HBIe− was proven effective in delivering the prescribed dose to the target area, while protecting the healthy skin.

AB - PurposeCertain radiation responsive skin diseases may develop symptoms on the upper or the lower half of the body. The concept of a novel Hemi-Body Electron Irradiation (HBIe−) technique, described in this work, provides a low cost, LINAC based, intermediate treatment option in between extremely localized and Total Skin irradiation techniques.Materials and methodsThe HBIe− technique, developed in our department, incorporates a custom crafted treatment chamber equipped with adjustable Pb shielding and a single electron beam in extended Source-Skin Distance (SSD) setup. The patient is positioned in 'Stanford' technique positions. The geometrical setup provides both optimal dose homogeneity and dose deposition up to a depth of 2 cm. To confirm this, the following characteristics were measured and evaluated: a) percentage depth dose (PDD) on the treatment plane produced by a single electron beam at perpendicular incidence for six fields at 'Stanford' angles, b) 2D profile of the entrance dose on the treatment plane produced by a single field and c) the total surface dose on an anthropomorphic phantom delivered by all 6 fields.ResultsThe resulting homogeneity of the surface dose in the treatment plane for an average patient was 5–6%, while surface dose homogeneity on the anthropomorphic phantom was 7% for both the upper and the lower HBIe− variants. The total PDD exhibits an almost linear decrease to a practical range of 2 g/cm2.ConclusionIn conclusion, HBIe− was proven effective in delivering the prescribed dose to the target area, while protecting the healthy skin.

KW - half-body skin irradiation

KW - Stanford technique

KW - Kaposi’s sarcoma

KW - t-cell lymphoma

UR - https://www.sciencedirect.com/journal/physica-medica

U2 - 10.1016/j.ejmp.2017.12.022

DO - 10.1016/j.ejmp.2017.12.022

M3 - Article

VL - 46

SP - 16

EP - 24

JO - Physica Medica

JF - Physica Medica

SN - 1120-1797

ER -

Delinikolas P, Patatoukas G, Kouloulias V, Dilvoi M, Plousi A, Efstathopoulos E et al. A novel Hemi-Body Irradiation technique using electron beams (HBIe). Physica Medica. 2018 Feb 28;46:16-24. https://doi.org/10.1016/j.ejmp.2017.12.022