A non-linear mathematical model representing the consequence of voltage decrement in the transverse tubular system on the measured conductance-voltage curve for the inward rectifier in frog skeletal muscle

T.E.  DeCoursey; John Dempster; O.F. Hutter

A non-linear mathematical model representing the consequence of voltage decrement in the transverse tubular system on the measured conductance-voltage curve for the inward rectifier in frog skeletal muscle

T.E. DeCoursey, John Dempster, O.F. Hutter

Strathclyde Institute Of Pharmacy And Biomedical Sciences

Research output: Contribution to journal › Conference Contribution › peer-review

Abstract

The inwardly rectifying potassium conductance in frog skeletal muscle resides largely in the transverse tubular system (TTS). In voltage-clamp experiments, the membrane potential of the TTS will in general not be the same as the surface potential, owing to voltage drop across the tubular luminal resistance; hence the measured total conductance-voltage relation is liable to differ from the intrinsic rectifying function.

Original language	English
Pages (from-to)	P7-P8
Number of pages	2
Journal	Journal of Physiology
Volume	329
Issue number	Suppl. 1
Publication status	Published - 1982
Event	The Physiological Society Glasgow Meeting - Glasgow, United Kingdom Duration: 16 Apr 1982 → 17 Apr 1982

Keywords

voltage
frog skeletal muscle
voltage-clamp experiments

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title = "A non-linear mathematical model representing the consequence of voltage decrement in the transverse tubular system on the measured conductance-voltage curve for the inward rectifier in frog skeletal muscle",

abstract = "The inwardly rectifying potassium conductance in frog skeletal muscle resides largely in the transverse tubular system (TTS). In voltage-clamp experiments, the membrane potential of the TTS will in general not be the same as the surface potential, owing to voltage drop across the tubular luminal resistance; hence the measured total conductance-voltage relation is liable to differ from the intrinsic rectifying function.",

keywords = "voltage, frog skeletal muscle, voltage-clamp experiments",

author = "T.E. DeCoursey and John Dempster and O.F. Hutter",

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volume = "329",

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journal = "Journal of Physiology",

issn = "0022-3751",

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note = "The Physiological Society Glasgow Meeting ; Conference date: 16-04-1982 Through 17-04-1982",

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A non-linear mathematical model representing the consequence of voltage decrement in the transverse tubular system on the measured conductance-voltage curve for the inward rectifier in frog skeletal muscle. / DeCoursey, T.E. ; Dempster, John; Hutter, O.F.
In: Journal of Physiology, Vol. 329, No. Suppl. 1, 1982, p. P7-P8.

Research output: Contribution to journal › Conference Contribution › peer-review

TY - JOUR

T1 - A non-linear mathematical model representing the consequence of voltage decrement in the transverse tubular system on the measured conductance-voltage curve for the inward rectifier in frog skeletal muscle

AU - DeCoursey, T.E.

AU - Dempster, John

AU - Hutter, O.F.

PY - 1982

Y1 - 1982

N2 - The inwardly rectifying potassium conductance in frog skeletal muscle resides largely in the transverse tubular system (TTS). In voltage-clamp experiments, the membrane potential of the TTS will in general not be the same as the surface potential, owing to voltage drop across the tubular luminal resistance; hence the measured total conductance-voltage relation is liable to differ from the intrinsic rectifying function.

AB - The inwardly rectifying potassium conductance in frog skeletal muscle resides largely in the transverse tubular system (TTS). In voltage-clamp experiments, the membrane potential of the TTS will in general not be the same as the surface potential, owing to voltage drop across the tubular luminal resistance; hence the measured total conductance-voltage relation is liable to differ from the intrinsic rectifying function.

KW - voltage

KW - frog skeletal muscle

KW - voltage-clamp experiments

UR - http://jp.physoc.org/content/329/supplement/1P.full.pdf+html

M3 - Conference Contribution

SN - 0022-3751

VL - 329

SP - P7-P8

JO - Journal of Physiology

JF - Journal of Physiology

IS - Suppl. 1

T2 - The Physiological Society Glasgow Meeting

Y2 - 16 April 1982 through 17 April 1982

ER -

A non-linear mathematical model representing the consequence of voltage decrement in the transverse tubular system on the measured conductance-voltage curve for the inward rectifier in frog skeletal muscle

Abstract

Keywords

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