Abstract
The inwardly rectifying potassium conductance in frog skeletal muscle resides largely in the transverse tubular system (TTS). In voltage-clamp experiments, the membrane potential of the TTS will in general not be the same as the surface potential, owing to voltage drop across the tubular luminal resistance; hence the measured total conductance-voltage relation is liable to differ from the intrinsic rectifying function.
| Original language | English |
|---|---|
| Pages (from-to) | P7-P8 |
| Number of pages | 2 |
| Journal | Journal of Physiology |
| Volume | 329 |
| Issue number | Suppl. 1 |
| Publication status | Published - 1982 |
| Event | The Physiological Society Glasgow Meeting - Glasgow, United Kingdom Duration: 16 Apr 1982 → 17 Apr 1982 |
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Keywords
- voltage
- frog skeletal muscle
- voltage-clamp experiments
Cite this
DeCoursey, T. E., Dempster, J., & Hutter, O. F. (1982). A non-linear mathematical model representing the consequence of voltage decrement in the transverse tubular system on the measured conductance-voltage curve for the inward rectifier in frog skeletal muscle. Journal of Physiology, 329(Suppl. 1), P7-P8.