A non-linear mathematical model representing the consequence of voltage decrement in the transverse tubular system on the measured conductance-voltage curve for the inward rectifier in frog skeletal muscle

T.E. DeCoursey, John Dempster, O.F. Hutter

Research output: Contribution to journalConference Contributionpeer-review


The inwardly rectifying potassium conductance in frog skeletal muscle resides largely in the transverse tubular system (TTS). In voltage-clamp experiments, the membrane potential of the TTS will in general not be the same as the surface potential, owing to voltage drop across the tubular luminal resistance; hence the measured total conductance-voltage relation is liable to differ from the intrinsic rectifying function.
Original languageEnglish
Pages (from-to)P7-P8
Number of pages2
JournalJournal of Physiology
Issue numberSuppl. 1
Publication statusPublished - 1982
EventThe Physiological Society Glasgow Meeting - Glasgow, United Kingdom
Duration: 16 Apr 198217 Apr 1982


  • voltage
  • frog skeletal muscle
  • voltage-clamp experiments

Cite this