A new drug vehicle - lipid coated biodegradable nanoparticles

J. Schäfer; Johannes Sitterberg; C. Ehrhardt; M.N.V. Ravi Kumar; Udo Bakowsky

doi:10.4028/www.scientific.net/AST.57.148

A new drug vehicle - lipid coated biodegradable nanoparticles

J. Schäfer, Johannes Sitterberg, C. Ehrhardt, M.N.V. Ravi Kumar, Udo Bakowsky

Strathclyde Institute Of Pharmacy And Biomedical Sciences

Research output: Contribution to journal › Article

10 Citations (Scopus)

Abstract

The preparation and charactersiation of novel lipid coated PLGA nanoparticles was investigated in the presented study. The size of the pure nanoparticles could be adjusted in dependence on the stabilizer content. The supported lipid bilayer surrounding the nanoparticles was formed by the liposome spreading technique. The Lipid- coated nanoparticles were characterised using Photon Correlation Spectroscopy (PCS) and atomic force microscopy (AFM) investigations. The bioadhesive properties was proofed in a cell culture model.

Language	English
Pages	148-153
Number of pages	5
Journal	Advances in Science and Technology
Volume	57
DOIs	10.4028/www.scientific.net/AST.57.148
Publication status	Published - Sep 2008

Fingerprint

Nanoparticles

Lipids

Pharmaceutical Preparations

Photon correlation spectroscopy

Lipid bilayers

Cell culture

Liposomes

Atomic force microscopy

polylactic acid-polyglycolic acid copolymer

Keywords

atomic force microscopy
biodegradable nanoparticles
lipid coating
PLGA

Cite this

Schäfer, J., Sitterberg, J., Ehrhardt, C., Kumar, M. N. V. R., & Bakowsky, U. (2008). A new drug vehicle - lipid coated biodegradable nanoparticles. Advances in Science and Technology, 57, 148-153. https://doi.org/10.4028/www.scientific.net/AST.57.148

Schäfer, J. ; Sitterberg, Johannes ; Ehrhardt, C. ; Kumar, M.N.V. Ravi ; Bakowsky, Udo. / A new drug vehicle - lipid coated biodegradable nanoparticles. In: Advances in Science and Technology. 2008 ; Vol. 57. pp. 148-153.

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Schäfer, J, Sitterberg, J, Ehrhardt, C, Kumar, MNVR & Bakowsky, U 2008, 'A new drug vehicle - lipid coated biodegradable nanoparticles' Advances in Science and Technology, vol. 57, pp. 148-153. https://doi.org/10.4028/www.scientific.net/AST.57.148

A new drug vehicle - lipid coated biodegradable nanoparticles. / Schäfer, J.; Sitterberg, Johannes; Ehrhardt, C.; Kumar, M.N.V. Ravi; Bakowsky, Udo.

In: Advances in Science and Technology, Vol. 57, 09.2008, p. 148-153.

Research output: Contribution to journal › Article

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