A new drug vehicle - lipid coated biodegradable nanoparticles

J. Schäfer, Johannes Sitterberg, C. Ehrhardt, M.N.V. Ravi Kumar, Udo Bakowsky

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

The preparation and charactersiation of novel lipid coated PLGA nanoparticles was investigated in the presented study. The size of the pure nanoparticles could be adjusted in dependence on the stabilizer content. The supported lipid bilayer surrounding the nanoparticles was formed by the liposome spreading technique. The Lipid- coated nanoparticles were characterised using Photon Correlation Spectroscopy (PCS) and atomic force microscopy (AFM) investigations. The bioadhesive properties was proofed in a cell culture model.
Original languageEnglish
Pages (from-to)148-153
Number of pages5
JournalAdvances in Science and Technology
Volume57
DOIs
Publication statusPublished - Sep 2008

Keywords

  • atomic force microscopy
  • biodegradable nanoparticles
  • lipid coating
  • PLGA

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