A new drug vehicle - lipid coated biodegradable nanoparticles

J. Schäfer, Johannes Sitterberg, C. Ehrhardt, M.N.V. Ravi Kumar, Udo Bakowsky

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The preparation and charactersiation of novel lipid coated PLGA nanoparticles was investigated in the presented study. The size of the pure nanoparticles could be adjusted in dependence on the stabilizer content. The supported lipid bilayer surrounding the nanoparticles was formed by the liposome spreading technique. The Lipid- coated nanoparticles were characterised using Photon Correlation Spectroscopy (PCS) and atomic force microscopy (AFM) investigations. The bioadhesive properties was proofed in a cell culture model.
LanguageEnglish
Pages148-153
Number of pages5
JournalAdvances in Science and Technology
Volume57
DOIs
Publication statusPublished - Sep 2008

Fingerprint

Nanoparticles
Lipids
Pharmaceutical Preparations
Photon correlation spectroscopy
Lipid bilayers
Cell culture
Liposomes
Atomic force microscopy
polylactic acid-polyglycolic acid copolymer

Keywords

  • atomic force microscopy
  • biodegradable nanoparticles
  • lipid coating
  • PLGA

Cite this

Schäfer, J., Sitterberg, J., Ehrhardt, C., Kumar, M. N. V. R., & Bakowsky, U. (2008). A new drug vehicle - lipid coated biodegradable nanoparticles. Advances in Science and Technology, 57, 148-153. https://doi.org/10.4028/www.scientific.net/AST.57.148
Schäfer, J. ; Sitterberg, Johannes ; Ehrhardt, C. ; Kumar, M.N.V. Ravi ; Bakowsky, Udo. / A new drug vehicle - lipid coated biodegradable nanoparticles. In: Advances in Science and Technology. 2008 ; Vol. 57. pp. 148-153.
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Schäfer, J, Sitterberg, J, Ehrhardt, C, Kumar, MNVR & Bakowsky, U 2008, 'A new drug vehicle - lipid coated biodegradable nanoparticles' Advances in Science and Technology, vol. 57, pp. 148-153. https://doi.org/10.4028/www.scientific.net/AST.57.148

A new drug vehicle - lipid coated biodegradable nanoparticles. / Schäfer, J.; Sitterberg, Johannes; Ehrhardt, C.; Kumar, M.N.V. Ravi; Bakowsky, Udo.

In: Advances in Science and Technology, Vol. 57, 09.2008, p. 148-153.

Research output: Contribution to journalArticle

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