A new approach to oligonucleotide labelling using Diels-Alder cycloadditions and detection by SERRS

L. Fruk, A. Grondin, W.E. Smith, D. Graham

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Diels-Alder cycloaddition has been used to add a benzotriazole azo dye to a diene tagged oligonucleotide to generate unique SERRS signals at 10 attomoles.
Original languageEnglish
Pages (from-to)2100-2101
Number of pages1
JournalChemical Communications (London)
Volume2002
Issue number18
DOIs
Publication statusPublished - 2002

Keywords

  • resonance raman-scattering
  • surface-enhanced raman
  • labeled dna
  • probes
  • spectroscopy
  • silver
  • acid

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