A micropatterned hydrogel platform for chemical synthesis and biological analysis

M Zourob, J E Gough, R V Ulijn

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

A polymer hydrogel platform for peptide arrays compatible both with solid-phase peptide synthesis (SPPS) conditions and the aqueous environment essential for biological assays is demonstrated. Micropatterning followed by multiple-step peptide synthesis in situ is followed by proof-of-concept on-chip biological assays involving cells and enzymes (see Figure and cover).

Original languageEnglish
Pages (from-to)655-659
Number of pages6
JournalAdvanced Materials
Volume18
Issue number5
DOIs
Publication statusPublished - 3 Mar 2006

Keywords

  • micropatterned hydrogel platform
  • chemical synthesis
  • biological analysis
  • peptides
  • arrays
  • biosensors
  • cells
  • enzymes
  • hydrogels
  • micropatterning

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