Abstract
A polymer hydrogel platform for peptide arrays compatible both with solid-phase peptide synthesis (SPPS) conditions and the aqueous environment essential for biological assays is demonstrated. Micropatterning followed by multiple-step peptide synthesis in situ is followed by proof-of-concept on-chip biological assays involving cells and enzymes (see Figure and cover).
| Original language | English |
|---|---|
| Pages (from-to) | 655-659 |
| Number of pages | 6 |
| Journal | Advanced Materials |
| Volume | 18 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 3 Mar 2006 |
Keywords
- micropatterned hydrogel platform
- chemical synthesis
- biological analysis
- peptides
- arrays
- biosensors
- cells
- enzymes
- hydrogels
- micropatterning