TY - JOUR
T1 - A low-cost, programmable device for versatile current delivery in iontophoresis applications
AU - Ching, T.S.S.
AU - Camilleri, I.
AU - Connolly, P.
PY - 2004
Y1 - 2004
N2 - Iontophoresis for the localised delivery of drugs through skin or for non-invasive, remote monitoring of patients by extraction of blood-borne components through skin could allow a new generation of medical devices to be developed for low-cost healthcare. Iontophoresis systems in existence today are generally not very portable and too expensive for all world markets. Accordingly, a low-cost, low-power, miniature and programmable device was developed and evaluated which can be programmed to deliver various current profiles during iontophoresis. It can provide a range of current (1-300 μA) of various signal waveforms (dc, pulsed dc, bipolar dc and pulsed bipolar dc) of the type required for iontophoresis. Evaluation showed that this device provides for precise regulation of the magnitude and waveform of a current. The current can be maintained over a wide range of impedance, important for use in medical application, and is independent of the battery voltage.
AB - Iontophoresis for the localised delivery of drugs through skin or for non-invasive, remote monitoring of patients by extraction of blood-borne components through skin could allow a new generation of medical devices to be developed for low-cost healthcare. Iontophoresis systems in existence today are generally not very portable and too expensive for all world markets. Accordingly, a low-cost, low-power, miniature and programmable device was developed and evaluated which can be programmed to deliver various current profiles during iontophoresis. It can provide a range of current (1-300 μA) of various signal waveforms (dc, pulsed dc, bipolar dc and pulsed bipolar dc) of the type required for iontophoresis. Evaluation showed that this device provides for precise regulation of the magnitude and waveform of a current. The current can be maintained over a wide range of impedance, important for use in medical application, and is independent of the battery voltage.
KW - iontophoresis
KW - drugs
KW - bioengineering
KW - medicine
KW - actuators
UR - http://dx.doi.org/10.1016/j.snb.2004.07.022
U2 - 10.1016/j.snb.2004.07.022
DO - 10.1016/j.snb.2004.07.022
M3 - Article
SN - 0925-4005
VL - 106
SP - 534
EP - 540
JO - Sensors and Actuators B: Chemical
JF - Sensors and Actuators B: Chemical
IS - 2
ER -