Medical implant associated infection is an ongoing problem, which can be particularly problematic when infection pathogenesis involves formation of bacterial biofilms. Biodegradable polymer drug delivery technology may be of use in some devices as a means of delivering a high local dose of antimicrobial drug. In this study the broad-spectrum antibiotic rifampicin was formulated with the polymer PLGA (Poly(D,L-lactic-co-glycolic acid (65:35)) and the in vitro drug release and activity analysed.
|Publication status||Published - 6 Sep 2018|
|Event||BioMedEng18 - Imperial College, London, United Kingdom|
Duration: 6 Sep 2018 → 7 Sep 2018
|Period||6/09/18 → 7/09/18|
- medical implant
- bacterial biofilms
- drug delivery technology