Projects per year
Abstract
The ability to form artificial lipid membranes in a reliable, high-throughput lab-on-a-chip format has the potential to advance membrane protein studies and the development of sensitive molecular biosensors, ultimately impacting on the development of novel and low-cost synthetic approaches to drug screening. Existing methods are limited in terms of their automation, throughput and ease of use. We have developed a microfluidic system that allows the formation, alternation, desired positioning and long-term storage of arrays of droplet-interface-bilayers (DIBs). By encapsulating the desired cocktail of liposomes and metabolites into phospholipid-stabilized water-in-oil (W/O) droplets, hundreds of DIBs were characterized using fluorescence-based assays.
| Original language | English |
|---|---|
| Number of pages | 3 |
| Publication status | Published - 31 Oct 2013 |
| Event | 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences - MicroTAS 2013 - Freiburg, Germany Duration: 27 Oct 2013 → 31 Oct 2013 http://microtasconferences.org/microtas2013/ |
Conference
| Conference | 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences - MicroTAS 2013 |
|---|---|
| Abbreviated title | MicroTAS 2013 |
| Country/Territory | Germany |
| City | Freiburg |
| Period | 27/10/13 → 31/10/13 |
| Internet address |
Keywords
- microfluidics
- lab - on - a - chip
- passive channel networks
- droplet - interface - bilayers
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Dive into the research topics of 'A high-throughput microfluidic system for the simultaneous formation of droplet-interface bilayer arrays'. Together they form a unique fingerprint.Projects
- 1 Finished
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EPSRC DOCTORAL TRAINING GRANT | Schlicht, Barbara
Zagnoni, M., Uttamchandani, D. & Schlicht, B.
EPSRC (Engineering and Physical Sciences Research Council)
1/10/11 → 25/09/19
Project: Research Studentship - Internally Allocated