A fluorescence study of the structure and kinetics of eumelanin formation

Jens Sutter; Tereza Bidlakova; Vlastimil Fidler; Jan Karolin; David Birch

A fluorescence study of the structure and kinetics of eumelanin formation

Jens Sutter, Tereza Bidlakova, Vlastimil Fidler, Jan Karolin, David Birch

Research output: Contribution to conference › Poster

Abstract

Melanin is an important pigment present in skin, hair, the eye and the brain. Although the constituents of melanin are quite well-known, its detailed structure has so far eluded all types of spectroscopy. Here we use Thioflavin T (ThT) fluorescence to provide evidence for a sheet like structure and reveal for the first time eumelanin’s synthesis kinetics. Using the dye Congo Red, we support the kinetics seen with ThT.

Original language	English
Publication status	Published - 11 Sept 2011
Event	MAF 11 - Duration: 6 Sept 2009 → 9 Sept 2009

Other

Other	MAF 11
Period	6/09/09 → 9/09/09

Keywords

eumelanin
fluorescence
thioflavin T
Congo Red

Cite this

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title = "A fluorescence study of the structure and kinetics of eumelanin formation",

abstract = "Melanin is an important pigment present in skin, hair, the eye and the brain. Although the constituents of melanin are quite well-known, its detailed structure has so far eluded all types of spectroscopy. Here we use Thioflavin T (ThT) fluorescence to provide evidence for a sheet like structure and reveal for the first time eumelanin{\textquoteright}s synthesis kinetics. Using the dye Congo Red, we support the kinetics seen with ThT. ",

keywords = "eumelanin, fluorescence, thioflavin T, Congo Red",

author = "Jens Sutter and Tereza Bidlakova and Vlastimil Fidler and Jan Karolin and David Birch",

year = "2011",

month = sep,

day = "11",

language = "English",

note = "MAF 11 ; Conference date: 06-09-2009 Through 09-09-2009",

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TY - CONF

T1 - A fluorescence study of the structure and kinetics of eumelanin formation

AU - Sutter, Jens

AU - Bidlakova, Tereza

AU - Fidler, Vlastimil

AU - Karolin, Jan

AU - Birch, David

PY - 2011/9/11

Y1 - 2011/9/11

N2 - Melanin is an important pigment present in skin, hair, the eye and the brain. Although the constituents of melanin are quite well-known, its detailed structure has so far eluded all types of spectroscopy. Here we use Thioflavin T (ThT) fluorescence to provide evidence for a sheet like structure and reveal for the first time eumelanin’s synthesis kinetics. Using the dye Congo Red, we support the kinetics seen with ThT.

AB - Melanin is an important pigment present in skin, hair, the eye and the brain. Although the constituents of melanin are quite well-known, its detailed structure has so far eluded all types of spectroscopy. Here we use Thioflavin T (ThT) fluorescence to provide evidence for a sheet like structure and reveal for the first time eumelanin’s synthesis kinetics. Using the dye Congo Red, we support the kinetics seen with ThT.

KW - eumelanin

KW - fluorescence

KW - thioflavin T

KW - Congo Red

M3 - Poster

T2 - MAF 11

Y2 - 6 September 2009 through 9 September 2009

ER -

A fluorescence study of the structure and kinetics of eumelanin formation

Abstract

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Keywords

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