A fluorescence study of the structure and kinetics of eumelanin formation

Jens Sutter, Tereza Bidlakova, Vlastimil Fidler, Jan Karolin, David Birch

Research output: Contribution to conferencePoster

Abstract

Melanin is an important pigment present in skin, hair, the eye and the brain. Although the constituents of melanin are quite well-known, its detailed structure has so far eluded all types of spectroscopy. Here we use Thioflavin T (ThT) fluorescence to provide evidence for a sheet like structure and reveal for the first time eumelanin’s synthesis kinetics. Using the dye Congo Red, we support the kinetics seen with ThT.
LanguageEnglish
Publication statusPublished - 11 Sep 2011
EventMAF 11 -
Duration: 6 Sep 20099 Sep 2009

Other

OtherMAF 11
Period6/09/099/09/09

Fingerprint

melanin
fluorescence
hair
kinetics
pigments
brain
dyes
synthesis
spectroscopy

Keywords

  • eumelanin
  • fluorescence
  • thioflavin T
  • Congo Red

Cite this

Sutter, J., Bidlakova, T., Fidler, V., Karolin, J., & Birch, D. (2011). A fluorescence study of the structure and kinetics of eumelanin formation. Poster session presented at MAF 11, .
Sutter, Jens ; Bidlakova, Tereza ; Fidler, Vlastimil ; Karolin, Jan ; Birch, David. / A fluorescence study of the structure and kinetics of eumelanin formation. Poster session presented at MAF 11, .
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title = "A fluorescence study of the structure and kinetics of eumelanin formation",
abstract = "Melanin is an important pigment present in skin, hair, the eye and the brain. Although the constituents of melanin are quite well-known, its detailed structure has so far eluded all types of spectroscopy. Here we use Thioflavin T (ThT) fluorescence to provide evidence for a sheet like structure and reveal for the first time eumelanin’s synthesis kinetics. Using the dye Congo Red, we support the kinetics seen with ThT.",
keywords = "eumelanin, fluorescence, thioflavin T, Congo Red",
author = "Jens Sutter and Tereza Bidlakova and Vlastimil Fidler and Jan Karolin and David Birch",
year = "2011",
month = "9",
day = "11",
language = "English",
note = "MAF 11 ; Conference date: 06-09-2009 Through 09-09-2009",

}

Sutter, J, Bidlakova, T, Fidler, V, Karolin, J & Birch, D 2011, 'A fluorescence study of the structure and kinetics of eumelanin formation' MAF 11, 6/09/09 - 9/09/09, .

A fluorescence study of the structure and kinetics of eumelanin formation. / Sutter, Jens; Bidlakova, Tereza; Fidler, Vlastimil; Karolin, Jan; Birch, David.

2011. Poster session presented at MAF 11, .

Research output: Contribution to conferencePoster

TY - CONF

T1 - A fluorescence study of the structure and kinetics of eumelanin formation

AU - Sutter, Jens

AU - Bidlakova, Tereza

AU - Fidler, Vlastimil

AU - Karolin, Jan

AU - Birch, David

PY - 2011/9/11

Y1 - 2011/9/11

N2 - Melanin is an important pigment present in skin, hair, the eye and the brain. Although the constituents of melanin are quite well-known, its detailed structure has so far eluded all types of spectroscopy. Here we use Thioflavin T (ThT) fluorescence to provide evidence for a sheet like structure and reveal for the first time eumelanin’s synthesis kinetics. Using the dye Congo Red, we support the kinetics seen with ThT.

AB - Melanin is an important pigment present in skin, hair, the eye and the brain. Although the constituents of melanin are quite well-known, its detailed structure has so far eluded all types of spectroscopy. Here we use Thioflavin T (ThT) fluorescence to provide evidence for a sheet like structure and reveal for the first time eumelanin’s synthesis kinetics. Using the dye Congo Red, we support the kinetics seen with ThT.

KW - eumelanin

KW - fluorescence

KW - thioflavin T

KW - Congo Red

M3 - Poster

ER -

Sutter J, Bidlakova T, Fidler V, Karolin J, Birch D. A fluorescence study of the structure and kinetics of eumelanin formation. 2011. Poster session presented at MAF 11, .