A direct and useful route to difluoroacylsilanes and difluoroacylstannanes and their potential for the generation of structurally diverse difluoroketones

Maxime R Garayt, Jonathan Percy

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Allyl trifluoroethyl ethers 2a–2d were prepared; each underwent efficient dehydrofluorination/metallation and trapping to afford a range of difluoroenol silanes and stannanes which rearranged easily and efficiently to the acyl metals. Fluoride-mediated benzylation and allylation of an acylsilane, and Stille coupling of the vinyl- and acyl-stannane were achieved in moderate to good yield.
Original languageEnglish
Pages (from-to)6377-6380
Number of pages4
JournalTetrahedron Letters
Volume42
Issue number36
DOIs
Publication statusPublished - 2001

Keywords

  • dehydrofluorination
  • metallation
  • difluoroenol silanes
  • Allyl trifluoroethyl ethers

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