A computer simulation of the transmission dynamics and the effects of duration of immunity and survival of persistently infected animals on the spread of bovine viral diarrhoea virus in dairy cattle

G. Innocent, I. Morrison, J. Brownlie, G. Gettinby

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

This paper describes a computer model that mimics the spread of bovine viral diarrhoea virus (BVDV) infection through a closed herd. The model is able to simulate the spread of infection when a persistently infected (PI) animal is introduced into an infection-free herd, and it is used to investigate the role of persistently infected animals, seroconverting animals, loss of PI calves and duration of immunity on the level of infection within the herd. Under typical management conditions one persistently infected animal poses a real threat to a herd, and the prospect of the herd becoming infection free in a 10-year period without intervention is remote. Seroconverting animals are found to be an important source of infection in herds with few immune animals. The increased loss of PI calves is likely to restrict the numbers of PI animals in a herd, and loss of immunity is important since it increases the possibility of a PI calf being born.
LanguageEnglish
Pages91-100
Number of pages9
JournalInfection and Epidemiology
Volume119
Issue number1
DOIs
Publication statusPublished - Aug 1997

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Bovine Viral Diarrhea Viruses
Computer Simulation
Immunity
Infection
Herd Immunity
Virus Diseases

Keywords

  • computer simulation
  • transmission dynamics
  • bovine viral diarrhoea virus
  • dairy cattle

Cite this

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A computer simulation of the transmission dynamics and the effects of duration of immunity and survival of persistently infected animals on the spread of bovine viral diarrhoea virus in dairy cattle. / Innocent, G.; Morrison, I.; Brownlie, J.; Gettinby, G.

In: Infection and Epidemiology, Vol. 119, No. 1, 08.1997, p. 91-100.

Research output: Contribution to journalArticle

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