A CMOS active pixel sensor for retinal stimulation

ML Prydderch; MJ French; K Mathieson; C Adams; D Gunning; J Laudanski; JD Morrison; AR Moodie; J Sinclair

doi:10.1117/12.641165

A CMOS active pixel sensor for retinal stimulation

ML Prydderch, MJ French, K Mathieson, C Adams, D Gunning, J Laudanski, JD Morrison, AR Moodie, J Sinclair

Research output: Contribution to conference › Paper

4 Citations (Scopus)

Abstract

Degenerative photoreceptor diseases, such as age-related
macular degeneration and retinitis pigmentosa, are the most common causes of blindness in the western world. A potential cure is to use a microelectronic retinal prosthesis to provide electrical stimulation to the remaining healthy retinal cells. We describe a prototype CMOS Active Pixel Sensor capable of detecting a visual scene and translating it into a train of electrical pulses for stimulation of the retina. The sensor consists of a 10 x 10 array of 100 micron square pixels fabricated on a 0.35 micron CMOS process. Light incident upon each pixel is converted into output current pulse trains with a frequency related to the light intensity. These outputs are connected to a biocompatible microelectrode array for contact to the retinal cells. The flexible design allows experimentation with signal amplitudes and frequencies in order to determine the most appropriate stimulus for the retina. Neural processing in the retina can be studied by using the sensor in conjunction with a Field Programmable Gate Array (FPGA) programmed to behave as a neural network. The sensor has been integrated into a test system designed for studying retinal response. We present the most recent results obtained from this sensor.

Original language	English
Pages	6803-6803
Number of pages	1
DOIs	https://doi.org/10.1117/12.641165
Publication status	Published - 18 Jan 2006
Event	Conference on Sensors, Cameras and Systems for Scientific/Industrial Applications - San Jose, United States Duration: 17 Jan 2006 → 19 Jan 2006

Conference

Conference	Conference on Sensors, Cameras and Systems for Scientific/Industrial Applications
Country	United States
City	San Jose
Period	17/01/06 → 19/01/06

Keywords

retinal stimulation
pixel sensor

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Prydderch, ML., French, MJ., Mathieson, K., Adams, C., Gunning, D., Laudanski, J., ... Sinclair, J. (2006). A CMOS active pixel sensor for retinal stimulation. 6803-6803. Paper presented at Conference on Sensors, Cameras and Systems for Scientific/Industrial Applications , San Jose, United States. https://doi.org/10.1117/12.641165

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title = "A CMOS active pixel sensor for retinal stimulation",

abstract = "Degenerative photoreceptor diseases, such as age-related macular degeneration and retinitis pigmentosa, are the most common causes of blindness in the western world. A potential cure is to use a microelectronic retinal prosthesis to provide electrical stimulation to the remaining healthy retinal cells. We describe a prototype CMOS Active Pixel Sensor capable of detecting a visual scene and translating it into a train of electrical pulses for stimulation of the retina. The sensor consists of a 10 x 10 array of 100 micron square pixels fabricated on a 0.35 micron CMOS process. Light incident upon each pixel is converted into output current pulse trains with a frequency related to the light intensity. These outputs are connected to a biocompatible microelectrode array for contact to the retinal cells. The flexible design allows experimentation with signal amplitudes and frequencies in order to determine the most appropriate stimulus for the retina. Neural processing in the retina can be studied by using the sensor in conjunction with a Field Programmable Gate Array (FPGA) programmed to behave as a neural network. The sensor has been integrated into a test system designed for studying retinal response. We present the most recent results obtained from this sensor.",

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author = "ML Prydderch and MJ French and K Mathieson and C Adams and D Gunning and J Laudanski and JD Morrison and AR Moodie and J Sinclair",

note = "Conference on Sensors, Cameras and Systems for Scientific/Industrial Applications VII, San Jose, CA, JAN 17-19, 2006; Conference on Sensors, Cameras and Systems for Scientific/Industrial Applications ; Conference date: 17-01-2006 Through 19-01-2006",

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Prydderch, ML, French, MJ, Mathieson, K, Adams, C, Gunning, D, Laudanski, J, Morrison, JD, Moodie, AR & Sinclair, J 2006, 'A CMOS active pixel sensor for retinal stimulation', Paper presented at Conference on Sensors, Cameras and Systems for Scientific/Industrial Applications , San Jose, United States, 17/01/06 - 19/01/06 pp. 6803-6803. https://doi.org/10.1117/12.641165

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AU - Adams, C

AU - Gunning, D

AU - Laudanski, J

AU - Morrison, JD

AU - Moodie, AR

AU - Sinclair, J

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N2 - Degenerative photoreceptor diseases, such as age-related macular degeneration and retinitis pigmentosa, are the most common causes of blindness in the western world. A potential cure is to use a microelectronic retinal prosthesis to provide electrical stimulation to the remaining healthy retinal cells. We describe a prototype CMOS Active Pixel Sensor capable of detecting a visual scene and translating it into a train of electrical pulses for stimulation of the retina. The sensor consists of a 10 x 10 array of 100 micron square pixels fabricated on a 0.35 micron CMOS process. Light incident upon each pixel is converted into output current pulse trains with a frequency related to the light intensity. These outputs are connected to a biocompatible microelectrode array for contact to the retinal cells. The flexible design allows experimentation with signal amplitudes and frequencies in order to determine the most appropriate stimulus for the retina. Neural processing in the retina can be studied by using the sensor in conjunction with a Field Programmable Gate Array (FPGA) programmed to behave as a neural network. The sensor has been integrated into a test system designed for studying retinal response. We present the most recent results obtained from this sensor.

AB - Degenerative photoreceptor diseases, such as age-related macular degeneration and retinitis pigmentosa, are the most common causes of blindness in the western world. A potential cure is to use a microelectronic retinal prosthesis to provide electrical stimulation to the remaining healthy retinal cells. We describe a prototype CMOS Active Pixel Sensor capable of detecting a visual scene and translating it into a train of electrical pulses for stimulation of the retina. The sensor consists of a 10 x 10 array of 100 micron square pixels fabricated on a 0.35 micron CMOS process. Light incident upon each pixel is converted into output current pulse trains with a frequency related to the light intensity. These outputs are connected to a biocompatible microelectrode array for contact to the retinal cells. The flexible design allows experimentation with signal amplitudes and frequencies in order to determine the most appropriate stimulus for the retina. Neural processing in the retina can be studied by using the sensor in conjunction with a Field Programmable Gate Array (FPGA) programmed to behave as a neural network. The sensor has been integrated into a test system designed for studying retinal response. We present the most recent results obtained from this sensor.

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