A CFD level-set method for soft tissue growth: theory and fundamental equations

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Abstract

A level-set method, specifically conceived for the case of soft organic tissue growth from feeding solutions, is introduced and described in detail. The model can handle the morphological evolution of the organic specimen under the influence of external convection (fluid-dynamics of the bioreactor). The analogies and differences between this technique and a previous volume of fraction method are discussed pointing out advantages and limitations of both formulations.
Original languageEnglish
Pages (from-to)185-190
Number of pages6
JournalJournal of Biomechanics
Volume38
Issue number1
DOIs
Publication statusPublished - 9 Apr 2004

Keywords

  • soft tissue growth
  • bioreactor
  • tissue engineering
  • growth kinetics
  • fluid motion
  • mathematical models
  • moving boundary method
  • morphology evolution
  • rotating vessel

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