A catemeric crystal structure of cyheptamide undergoes a transformation in the solid-state upon heating to produce a dimer-based form whose structure has been determined from laboratory X-ray powder diffraction (XRPD) data, thereby providing the first conclusive evidence of a carbamazepine analogue crystallising in both hydrogen bonded motifs.
- biomedical sciences
Florence, A. J., Shankland, K., Gelbrich, T., Hursthouse, M. B., Shankland, N., Johnston, A., ... Leech, C. K. (2008). A catemer-to-dimer structural transformation in cyheptamide. CrystEngComm, 10, 26-28. https://doi.org/10.1039/b712547j