A 256 × 8 SPAD line sensor for time resolved fluorescence and raman sensing

Nikola Krstajić; Richard Walker; James Levitt; Simon P. Poland; David Li; Simon Ameer-Beg; Robert Henderson

doi:10.1109/ESSCIRC.2014.6942042

A 256 × 8 SPAD line sensor for time resolved fluorescence and raman sensing

Nikola Krstajić, Richard Walker, James Levitt, Simon P. Poland, David Li, Simon Ameer-Beg, Robert Henderson

Strathclyde Institute Of Pharmacy And Biomedical Sciences

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution book

8 Citations (Scopus)

Abstract

A 256 × 8 single photon avalanche diode (SPAD) time-resolved single photon counting (TCPSC) line sensor enables both fluorescence and Raman spectroscopy in a single device. The 23.78μm pitch, 46.8% fill-factor SPAD array is implemented in a 0.13μm CMOS image sensor process. Integrating time to digital converters (TDCs) implement on-chip mono-exponential fluorescence lifetime pre-calculation allowing timing of 65k photons/pixel at 500s-1 line rate at 40ps resolution using centre-of-mass method (CMM). TCSPC histograms may also be generated with 320ps bin resolution for multi-exponential analysis.

Original language	English
Title of host publication	European Solid State Circuits Conference (ESSCIRC), ESSCIRC 2014 - 40th
Publisher	IEEE
Pages	143-146
Number of pages	4
ISBN (Print)	9781479956944
DOIs	https://doi.org/10.1109/ESSCIRC.2014.6942042
Publication status	Published - 22 Sept 2014
Event	40th European Solid-State Circuits Conference - Palazzo del Casinò, Venice, Italy Duration: 22 Sept 2014 → 26 Sept 2014 http://www.esscirc2014.org/en/sistemacongressi/european-solid-state-circuits-conference-2014/website/home/

Publication series

Name
ISSN (Print)	1930-8833

Conference

Conference	40th European Solid-State Circuits Conference
Country/Territory	Italy
City	Venice
Period	22/09/14 → 26/09/14
Internet address	http://www.esscirc2014.org/en/sistemacongressi/european-solid-state-circuits-conference-2014/website/home/

Keywords

time-digital conversion
avalanche diodes
CMOS image sensors
fluorescence spectroscopy
photon counting
Raman spectra
time resolved spectra
arrays
detectors
image resolution

Access to Document

10.1109/ESSCIRC.2014.6942042

Cite this

@inproceedings{2fae1f94c8e54f919d90ea4f72b58460,

title = "A 256 × 8 SPAD line sensor for time resolved fluorescence and raman sensing",

abstract = "A 256 × 8 single photon avalanche diode (SPAD) time-resolved single photon counting (TCPSC) line sensor enables both fluorescence and Raman spectroscopy in a single device. The 23.78μm pitch, 46.8\% fill-factor SPAD array is implemented in a 0.13μm CMOS image sensor process. Integrating time to digital converters (TDCs) implement on-chip mono-exponential fluorescence lifetime pre-calculation allowing timing of 65k photons/pixel at 500s-1 line rate at 40ps resolution using centre-of-mass method (CMM). TCSPC histograms may also be generated with 320ps bin resolution for multi-exponential analysis.",

keywords = "time-digital conversion, avalanche diodes, CMOS image sensors, fluorescence spectroscopy, photon counting, Raman spectra, time resolved spectra, arrays, detectors, image resolution",

author = "Nikola Krstaji{\'c} and Richard Walker and James Levitt and Poland, \{Simon P.\} and David Li and Simon Ameer-Beg and Robert Henderson",

year = "2014",

month = sep,

day = "22",

doi = "10.1109/ESSCIRC.2014.6942042",

language = "English",

isbn = "9781479956944",

publisher = "IEEE",

pages = "143--146",

booktitle = "European Solid State Circuits Conference (ESSCIRC), ESSCIRC 2014 - 40th",

note = "40th European Solid-State Circuits Conference ; Conference date: 22-09-2014 Through 26-09-2014",

url = "http://www.esscirc2014.org/en/sistemacongressi/european-solid-state-circuits-conference-2014/website/home/",

}

Krstajić, N, Walker, R, Levitt, J, Poland, SP, Li, D, Ameer-Beg, S & Henderson, R 2014, A 256 × 8 SPAD line sensor for time resolved fluorescence and raman sensing. in European Solid State Circuits Conference (ESSCIRC), ESSCIRC 2014 - 40th. IEEE, pp. 143-146, 40th European Solid-State Circuits Conference, Venice, Italy, 22/09/14. https://doi.org/10.1109/ESSCIRC.2014.6942042

TY - GEN

T1 - A 256 × 8 SPAD line sensor for time resolved fluorescence and raman sensing

AU - Krstajić, Nikola

AU - Walker, Richard

AU - Levitt, James

AU - Poland, Simon P.

AU - Li, David

AU - Ameer-Beg, Simon

AU - Henderson, Robert

PY - 2014/9/22

Y1 - 2014/9/22

N2 - A 256 × 8 single photon avalanche diode (SPAD) time-resolved single photon counting (TCPSC) line sensor enables both fluorescence and Raman spectroscopy in a single device. The 23.78μm pitch, 46.8% fill-factor SPAD array is implemented in a 0.13μm CMOS image sensor process. Integrating time to digital converters (TDCs) implement on-chip mono-exponential fluorescence lifetime pre-calculation allowing timing of 65k photons/pixel at 500s-1 line rate at 40ps resolution using centre-of-mass method (CMM). TCSPC histograms may also be generated with 320ps bin resolution for multi-exponential analysis.

AB - A 256 × 8 single photon avalanche diode (SPAD) time-resolved single photon counting (TCPSC) line sensor enables both fluorescence and Raman spectroscopy in a single device. The 23.78μm pitch, 46.8% fill-factor SPAD array is implemented in a 0.13μm CMOS image sensor process. Integrating time to digital converters (TDCs) implement on-chip mono-exponential fluorescence lifetime pre-calculation allowing timing of 65k photons/pixel at 500s-1 line rate at 40ps resolution using centre-of-mass method (CMM). TCSPC histograms may also be generated with 320ps bin resolution for multi-exponential analysis.

KW - time-digital conversion

KW - avalanche diodes

KW - CMOS image sensors

KW - fluorescence spectroscopy

KW - photon counting

KW - Raman spectra

KW - time resolved spectra

KW - arrays

KW - detectors

KW - image resolution

UR - http://www.esscirc2014.org/en/sistemacongressi/european-solid-state-circuits-conference-2014/website/home/

U2 - 10.1109/ESSCIRC.2014.6942042

DO - 10.1109/ESSCIRC.2014.6942042

M3 - Conference contribution book

SN - 9781479956944

SP - 143

EP - 146

BT - European Solid State Circuits Conference (ESSCIRC), ESSCIRC 2014 - 40th

PB - IEEE

T2 - 40th European Solid-State Circuits Conference

Y2 - 22 September 2014 through 26 September 2014

ER -

A 256 × 8 SPAD line sensor for time resolved fluorescence and raman sensing

Abstract

Publication series

Conference

Keywords

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