Abstract
| Language | English |
|---|---|
| Pages | S390-S390 |
| Number of pages | 1 |
| Journal | Tissue Engineering, Parts A, B & C |
| Volume | 21 |
| Issue number | Part A |
| DOIs | |
| Publication status | Published - 1 Sep 2015 |
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Keywords
- stem cell printing
- tissue engineering
- pluripotent stem cells
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3D bioprinting of human pluripotent stem cells for tissue engineering. / Shu, Will; Faulkner-Jones, Alan John.
In: Tissue Engineering, Parts A, B & C, Vol. 21, No. Part A, 01.09.2015, p. S390-S390.Research output: Contribution to journal › Conference Contribution
TY - JOUR
T1 - 3D bioprinting of human pluripotent stem cells for tissue engineering
AU - Shu, Will
AU - Faulkner-Jones, Alan John
PY - 2015/9/1
Y1 - 2015/9/1
N2 - In recent years, the use of a simple inkjet technology for cell printing has triggered tremendous interest in the field of 3d biofab-rication or organ printing. A key challenge has been the development of printing processes which are both controllable and less harmful, in order to preserve cell and tissue viability and functions. In this talk, we will present the development of a valve-based stem cell printer that has been validated to print highly viable and functional human embryonic stem cells (h-ESCs) and induced pluripotent stem cells (h- iPSCs). 3D bioprinting based on both scaffold based (using different printable hydrogel materials) and scaffold-free (using hanging droplet technique) approaches will be discussed. This work demonstrates that the valve-based printing process is gentle enough to maintain stem cell viability, accurate enough to produce spheroids of uniform size and cell-containing hydrogel structures, and that printed cells maintain their pluripotency. In addition, our recent work on printing human stem cell derived liver tissues for animal-free drug testing applications will be presented.
AB - In recent years, the use of a simple inkjet technology for cell printing has triggered tremendous interest in the field of 3d biofab-rication or organ printing. A key challenge has been the development of printing processes which are both controllable and less harmful, in order to preserve cell and tissue viability and functions. In this talk, we will present the development of a valve-based stem cell printer that has been validated to print highly viable and functional human embryonic stem cells (h-ESCs) and induced pluripotent stem cells (h- iPSCs). 3D bioprinting based on both scaffold based (using different printable hydrogel materials) and scaffold-free (using hanging droplet technique) approaches will be discussed. This work demonstrates that the valve-based printing process is gentle enough to maintain stem cell viability, accurate enough to produce spheroids of uniform size and cell-containing hydrogel structures, and that printed cells maintain their pluripotency. In addition, our recent work on printing human stem cell derived liver tissues for animal-free drug testing applications will be presented.
KW - stem cell printing
KW - tissue engineering
KW - pluripotent stem cells
U2 - 10.1089/ten.tea.2015.5000.abstract
DO - 10.1089/ten.tea.2015.5000.abstract
M3 - Conference Contribution
VL - 21
SP - S390-S390
JO - Tissue Engineering, Parts A, B & C
T2 - Tissue Engineering, Parts A, B & C
JF - Tissue Engineering, Parts A, B & C
SN - 2152-4947
IS - Part A
ER -