3D biofabrication for tubular tissue engineering

Ian Holland, Jack Logan, Jiezhong Shi, Christopher McCormick, Dongsheng Liu, Wenmiao Shu

Research output: Contribution to journalArticlepeer-review

52 Citations (Scopus)
177 Downloads (Pure)


The therapeutic replacement of diseased tubular tissue is hindered by the availability and suitability of current donor, autologous and synthetically derived protheses. Artificially created, tissue engineered, constructs have the potential to alleviate these concerns with reduced auto-immune response, high anatomical accuracy, long term patency and growth potential. The advent of 3D bio-printing technology has further supplemented the technological toolbox, opening up new biofabrication research opportunities and expanding the therapeutic potential of the field. In this review, we highlight the challenges facing those seeking to create artificial tubular tissue with its associated complex macro and microscopic architecture. Current biofabrication approaches, including 3D printing techniques, are reviewed and future directions suggested.
Original languageEnglish
Number of pages12
JournalBio-Design and Manufacturing
Early online date23 May 2018
Publication statusE-pub ahead of print - 23 May 2018


  • tubular organs
  • tissue engineering
  • 3D printing
  • bio-inks


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