Abstract
In the title solvate, C17H20N4S· 2C3H8O, pairs of olanzapine molecules related by a centre of inversion stack along the a axis, forming columns, which are packed parallel to each other along the b axis, forming a sheet arrangement. The columns within these sheets are hydrogen bonded to each other through the propan-2-ol solvent molecules. The diazepine ring of the olanzapine exists in a puckered conformation with the thiophene and phenyl rings making a dihedral angle of 57.66 (7)° and the piperazine ring adopts a chair conformation with the methyl group in an equatorial position.
Original language | English |
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Pages (from-to) | o752-o753 |
Number of pages | 10 |
Journal | Acta Crystallographica Section E: Crystallographic Communications |
Volume | 69 |
Issue number | 5 |
Early online date | 20 Apr 2013 |
DOIs | |
Publication status | Published - 31 May 2013 |
Funding
RM thanks the Commonwealth Scholarship Commission for providing a scholarship.
Keywords
- crystallography
- olanzapine molecules
- propan-2-ol solvent molecules