1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene

Roy A. Kelly, Gabriela A. Grasa, Steven P. Nolan, David J. Nelson

Research output: Contribution to specialist publicationArticle

Abstract

Alternate Name: IPr.

Solubility: soluble in THF, hexane, toluene, ether, and most organic solvents.

Analysis of Reagent Purity: elemental microanalysis, NMR spectroscopy.

Preparative Methods: can be prepared under inert atmosphere3 utilizing dry, oxygen-free solvents.4 IPr·HCl2 and KOtBu were added to a NaH suspension in THF in the glove box (eq 1). The mixture was stirred for 1 h at room temperature, for 2 h at 60 °C, followed by overnight stirring at room temperature. THF was removed in vacuo, the product was extracted with hot hexanes, filtered through a pad of Celite, and the solvent removed in vacuo resulting in a white solid.2
LanguageEnglish
Specialist publicatione-EROS Encyclopaedia of Reagents for Organic Synthesis
PublisherJohn Wiley & Sons Inc.
DOIs
Publication statusPublished - 31 Mar 2016

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Hexanes
Diatomaceous Earth
Microanalysis
Toluene
Ether
Organic solvents
Nuclear magnetic resonance spectroscopy
Suspensions
Solubility
Oxygen
Temperature
1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene

Keywords

  • reagents
  • organic synthesis

Cite this

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1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene. / Kelly, Roy A.; Grasa, Gabriela A.; Nolan, Steven P.; Nelson, David J.

In: e-EROS Encyclopaedia of Reagents for Organic Synthesis, 31.03.2016.

Research output: Contribution to specialist publicationArticle

TY - GEN

T1 - 1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene

AU - Kelly, Roy A.

AU - Grasa, Gabriela A.

AU - Nolan, Steven P.

AU - Nelson, David J.

PY - 2016/3/31

Y1 - 2016/3/31

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AB - Alternate Name: IPr.Solubility: soluble in THF, hexane, toluene, ether, and most organic solvents.Analysis of Reagent Purity: elemental microanalysis, NMR spectroscopy.Preparative Methods: can be prepared under inert atmosphere3 utilizing dry, oxygen-free solvents.4 IPr·HCl2 and KOtBu were added to a NaH suspension in THF in the glove box (eq 1). The mixture was stirred for 1 h at room temperature, for 2 h at 60 °C, followed by overnight stirring at room temperature. THF was removed in vacuo, the product was extracted with hot hexanes, filtered through a pad of Celite, and the solvent removed in vacuo resulting in a white solid.2

KW - reagents

KW - organic synthesis

UR - http://onlinelibrary.wiley.com/book/10.1002/047084289X

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M3 - Article

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PB - John Wiley & Sons Inc.

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