Abstract
Surface enhanced Raman scattering (SERS) tags are in situ probes that can provide sensitive and selective probes for optical analysis in biological materials. Engineering tags for use in the near infrared (NIR) region is of particular interest since there is an uncongested spectral window for optical analysis due to the low background absorption and scattering from many molecules. An improved synthesis has resulted in the formation of hollow gold nanoshells (HGNs) with a localised surface plasmon resonance (LSPR) between 800 and 900 nm which provide effective SERS when excited at 1064 nm. Seven Raman reporters containing aromatic amine or thiol attachment groups were investigated. All were effective but 1,2-bis(4-pyridyl)ethylene (BPE) and 4,4-azopyridine (AZPY) provided the largest enhancement. At approximately monolayer coverage, these two reporters appear to pack with the main axis of the molecule perpendicular or nearly perpendicular to the surface giving strong SERS and thus providing effective 1064 nm gold SERS nanotags.
| Original language | English |
|---|---|
| Pages (from-to) | 1980-1986 |
| Number of pages | 7 |
| Journal | Physical Chemistry Chemical Physics |
| Volume | 17 |
| Issue number | 3 |
| Early online date | 27 Nov 2014 |
| DOIs | |
| Publication status | Published - 21 Jan 2015 |
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Keywords
- gold nanotags
- SERS nanoparticle tags
- optical analysis
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1064 nm SERS of NIR active hollow gold nanotags. / Kearns, H.; Shand, N. C.; Smith, W. E.; Faulds, K.; Graham, D.
In: Physical Chemistry Chemical Physics, Vol. 17, No. 3, 21.01.2015, p. 1980-1986.Research output: Contribution to journal › Article
TY - JOUR
T1 - 1064 nm SERS of NIR active hollow gold nanotags
AU - Kearns, H.
AU - Shand, N. C.
AU - Smith, W. E.
AU - Faulds, K.
AU - Graham, D.
PY - 2015/1/21
Y1 - 2015/1/21
N2 - Surface enhanced Raman scattering (SERS) tags are in situ probes that can provide sensitive and selective probes for optical analysis in biological materials. Engineering tags for use in the near infrared (NIR) region is of particular interest since there is an uncongested spectral window for optical analysis due to the low background absorption and scattering from many molecules. An improved synthesis has resulted in the formation of hollow gold nanoshells (HGNs) with a localised surface plasmon resonance (LSPR) between 800 and 900 nm which provide effective SERS when excited at 1064 nm. Seven Raman reporters containing aromatic amine or thiol attachment groups were investigated. All were effective but 1,2-bis(4-pyridyl)ethylene (BPE) and 4,4-azopyridine (AZPY) provided the largest enhancement. At approximately monolayer coverage, these two reporters appear to pack with the main axis of the molecule perpendicular or nearly perpendicular to the surface giving strong SERS and thus providing effective 1064 nm gold SERS nanotags.
AB - Surface enhanced Raman scattering (SERS) tags are in situ probes that can provide sensitive and selective probes for optical analysis in biological materials. Engineering tags for use in the near infrared (NIR) region is of particular interest since there is an uncongested spectral window for optical analysis due to the low background absorption and scattering from many molecules. An improved synthesis has resulted in the formation of hollow gold nanoshells (HGNs) with a localised surface plasmon resonance (LSPR) between 800 and 900 nm which provide effective SERS when excited at 1064 nm. Seven Raman reporters containing aromatic amine or thiol attachment groups were investigated. All were effective but 1,2-bis(4-pyridyl)ethylene (BPE) and 4,4-azopyridine (AZPY) provided the largest enhancement. At approximately monolayer coverage, these two reporters appear to pack with the main axis of the molecule perpendicular or nearly perpendicular to the surface giving strong SERS and thus providing effective 1064 nm gold SERS nanotags.
KW - gold nanotags
KW - SERS nanoparticle tags
KW - optical analysis
UR - http://www.scopus.com/inward/record.url?scp=84918779323&partnerID=8YFLogxK
U2 - 10.1039/c4cp04281f
DO - 10.1039/c4cp04281f
M3 - Article
VL - 17
SP - 1980
EP - 1986
JO - Physical Chemistry Chemical Physics
JF - Physical Chemistry Chemical Physics
SN - 1463-9076
IS - 3
ER -