α-Cyclodextrin/aminobenzoic acid binding in salt solutions at different pH: dependence on guest structure

Anastasia O. Romanova, Ekaterina Chibunova, Roman S. Kumeev, Maxim V. Fedorov, Irina V. Terekhova

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Influence of Na+ and K+ cations on α-cyclodextrin guest-host complex formation with isomeric aminobenzoic acids was examined at different pH and temperature of 298.15K by 1H NMR and calorimetry methods. More pronounced influence of Na+ on inclusion complex formation of α-CD with aminobenzoic acid anions compare to the effects of Na+ on α-CD complex formation with zwitterionic aminobenzoic acid molecules was revealed. For the first time, the dependence of salt effects on the structure, ionization and the hydration state of the guest molecule was demonstrated and analysed on the basis of the obtained thermodynamic parameters of complex formation and calculated free energy of hydration of different ionized forms of aminobenzoic acids.
LanguageEnglish
Pages255-258
Number of pages4
JournalInternational Journal of Biological Macromolecules
Volume57
DOIs
Publication statusPublished - 1 Jun 2013

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Aminobenzoates
Salts
Hydration
Calorimetry
Molecules
Thermodynamics
Free energy
Ionization
Anions
Cations
Nuclear magnetic resonance
Temperature
alpha-cyclodextrin

Keywords

  • cyclodextrin aminobenzoic acids
  • guest-host binding
  • hydration
  • inclusion complex formation
  • salt effect

Cite this

Romanova, Anastasia O. ; Chibunova, Ekaterina ; Kumeev, Roman S. ; Fedorov, Maxim V. ; Terekhova, Irina V. / α-Cyclodextrin/aminobenzoic acid binding in salt solutions at different pH : dependence on guest structure. In: International Journal of Biological Macromolecules. 2013 ; Vol. 57. pp. 255-258.
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α-Cyclodextrin/aminobenzoic acid binding in salt solutions at different pH : dependence on guest structure. / Romanova, Anastasia O. ; Chibunova, Ekaterina; Kumeev, Roman S.; Fedorov, Maxim V.; Terekhova, Irina V.

In: International Journal of Biological Macromolecules, Vol. 57, 01.06.2013, p. 255-258.

Research output: Contribution to journalArticle

TY - JOUR

T1 - α-Cyclodextrin/aminobenzoic acid binding in salt solutions at different pH

T2 - International Journal of Biological Macromolecules

AU - Romanova, Anastasia O.

AU - Chibunova, Ekaterina

AU - Kumeev, Roman S.

AU - Fedorov, Maxim V.

AU - Terekhova, Irina V.

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AB - Influence of Na+ and K+ cations on α-cyclodextrin guest-host complex formation with isomeric aminobenzoic acids was examined at different pH and temperature of 298.15K by 1H NMR and calorimetry methods. More pronounced influence of Na+ on inclusion complex formation of α-CD with aminobenzoic acid anions compare to the effects of Na+ on α-CD complex formation with zwitterionic aminobenzoic acid molecules was revealed. For the first time, the dependence of salt effects on the structure, ionization and the hydration state of the guest molecule was demonstrated and analysed on the basis of the obtained thermodynamic parameters of complex formation and calculated free energy of hydration of different ionized forms of aminobenzoic acids.

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