Research output per year
Research output per year
Research output
- 9 Article
Search results
-
2018
Failure of the anti-inflammatory parasitic worm product ES-62 to provide protection in mouse models of type I diabetes, multiple sclerosis, and inflammatory bowel disease
Doonan, J., Thomas, D., Wong, M. H., Ramage, H. J., Al-Riyami, L., Lumb, F. E., Bell, K. S., Fairlie-Clarke, K. J., Suckling, C. J., Michelsen, K. S., Jiang, H.-R., Cooke, A., Harnett, M. M. & Harnett, W., 17 Oct 2018, In: Molecules. 23, 10, 14 p., 2669.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Citations (Scopus)50 Downloads (Pure) -
Small molecule analogues of the parasitic worm product ES-62 interact with the TIR domain of MyD88 to inhibit pro-inflammatory signalling
Suckling, C. J., Alam, S., Olson, M. A., Saikh, K. U., Harnett, M. M. & Harnett, W., 1 Feb 2018, In: Scientific Reports. 8, 11 p., 2123.Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Citations (Scopus)60 Downloads (Pure) -
2016
Testing small molecule analogues of acanthocheilonema viteae immunomodulator ES-62 against clinically relevant allergens
Janicova, L., Rzepecka, J., Rodgers, D. T., Doonan, J., Bell, K., Lumb, F. E., Suckling, C. J., Harnett, M. M. & Harnett, W., 30 Jun 2016, In: Parasite Immunology. 38, 6, p. 340-351 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)73 Downloads (Pure) -
The parasitic worm-derived immunomodulator, ES-62 and its drug-like small molecule analogues exhibit therapeutic potential in a model of chronic asthma
Coltherd, J. C., Rodgers, D. T., Lawrie, R. E., Al-Riyami, L., Suckling, C. J., Harnett, W. & Harnett, M. M., 14 Jan 2016, In: Scientific Reports. 6, 14 p., 19224.Research output: Contribution to journal › Article › peer-review
Open AccessFile33 Citations (Scopus)121 Downloads (Pure) -
2015
Drug-like analogues of the parasitic worm-derived immunomodulator ES-62 are therapeutic in the MRL/Lpr model of systemic lupus erythematosus
Rodgers, D. T., Pineda, M. A., Suckling, C. J., Harnett, W. & Harnett, M. M., 1 Nov 2015, In: Lupus. 24, 13, p. 1437-1442 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile26 Citations (Scopus)87 Downloads (Pure) -
The role of individual protein kinase C isoforms in mouse mast cell function and their targeting by the immunomodulatory parasitic worm product, ES-62
Bell, K. S., Al-Riyami, L., Lumb, F. E., Britton, G. J., Poole, A. W., Williams, C. M., Braun, U., Leitges, M., Harnett, M. M. & Harnett, W., Nov 2015, In: Immunology Letters. 168, 1, p. 31-40 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)139 Downloads (Pure) -
Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter-regulation of the inflammasome
Rzepecka, J., Pineda, M. A., Al-Riyami, L., Rodgers, D. T., Huggan, J. K., Lumb, F. E., Khalaf, A. I., Meakin, P. J., Corbet, M., Ashford, M. L., Suckling, C. J., Harnett, M. M. & Harnett, W., 1 Jun 2015, In: Journal of Autoimmunity. 60, p. 59-73 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile70 Citations (Scopus)2309 Downloads (Pure) -
The parasitic worm product ES-62 targets myeloid differentiation factor 88-dependent effector mechanisms to suppress antinuclear antibody production and proteinuria in MRL/lpr mice
Rodgers, D. T., McGrath, M. A., Pineda, M. A., Al-Riyami, L., Rzepecka, J., Lumb, F., Harnett, W. & Harnett, M. M., 1 Apr 2015, In: Arthritis and Rheumatology. 67, 4, p. 1023-1035 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile46 Citations (Scopus)243 Downloads (Pure) -
2013
The helminth product, ES-62, protects against airway inflammation by resetting the Th cell phenotype
Rzepecka, J., Siebeke, I., Coltherd, J., Kean, D., Steiger, C., Al-Riyami, L., McSharry, C., Harnett, M. & Harnett, W., Mar 2013, In: International Journal for Parasitology. 43, 3-4, p. 211–223 13 p.Research output: Contribution to journal › Article › peer-review
File57 Citations (Scopus)135 Downloads (Pure)