Regulation of High Mobility Group Box 1 (HMGB1) protein from human microglial cells in response to thrombin

Cunningham, Margaret Rose (Principal Investigator)
Butler, Liam (Post Grad Student)

Strathclyde Institute Of Pharmacy And Biomedical Sciences

Project: Research

Description

The aim of this project was to investigate HMGB1-mediated microglial cell activity in response to thrombin as a potential mechanism of inflammation.

Short title	Thrombin-mediated HMGB1 regulation
Status	Finished
Effective start/end date	1/10/18 → 31/08/19

Keywords

GPCRs
Thrombin
HMGB1
Microglia
Inflammation

Molecular mechanisms of HMGB1 release from platelets and its implication in chemotherapy-induced peripheral neuropathy and thrombosis
Domoto, R. (Principal Investigator), Cunningham, M. R. (Principal Investigator) & Kawabata, A. (Co-investigator)
1/09/19 → 31/08/20
Project: Research Fellowship
Regulation of High Mobility Group Box 1 (HMGB1) protein from human microglial cells in response to thrombin
Butler, L. (Post Grad Student) & Cunningham, M. R. (Principal Investigator)
1/10/18 → 30/06/19
Project: Research